𝗣𝗵𝘆𝘀𝗶𝗰𝘀 𝗼𝗳 𝗹𝗶𝗳𝗲: We are excited to share our recent work investigating how ultra-weak protein-protein interactions can modulate behavior in the cytoplasmic proteome of 𝘔. 𝘨𝘦𝘯𝘪𝘵𝘢𝘭𝘪𝘶𝘮. biorxiv.org/content/10.110…

We are excited to share the publication of our work "Colloidal Physics Modeling Reveals How Per-Ribosome Productivity Increases with Growth Rate in Escherichia coli" in mBio. Congrats to Akshay and the rest of the team! Check it out at doi.org/10.1128/mbio.0…

Exciting news! Alp Mehmet Sunol has published his work "Confined Brownian suspensions: Equilibrium diffusion, thermodynamics, and rheology" in Journal of Rheology! Please find it here: doi.org/10.1122/8.0000…

The Zia Lab is hiring! Postdocs and Grad Students are needed for new Sloan Foundation Grant aimed at modeling the colloidal physics that instantiates life itself in the minimal biological cell. Details can be found here: sloan.org/programs/resea…

11:30 AM at APS, join us for an exciting session: “New physics based perspectives in building and understanding biological cells” Access ROOM 238 via ROOM 205! invited speakers are Roseanna Zia, Kate Adamala , John Glass, Roseanna Zia , Antonio Calavera, Sumitaba Brahmachari

Come see our talk at ICR on Friday at 11:50 with exciting results about two step yield in colloidal gels!

𝗣𝗵𝘆𝘀𝗶𝗰𝘀 𝗼𝗳 𝗹𝗶𝗳𝗲: We are excited to share our new preprint on 3D diffusion in live E. coli where we show how colloidal physics regulate life-essential processes in biological cells. Check out the paper and video at lnkd.in/g2GV4Ypv.

Check out our expanded model for Confined Stokesian dynamics with novel functions for rheology, just published in Journal of Fluid Mechanics. Check out the paper at doi.org/10.1017/jfm.20…

Excited to share our accepted Annual Reviews article, "The matter/life nexus in biological cells". We cast a wide net into cellular biology, biophysics, and genetic approaches to defining life, toward understanding of the materiality of cellular life: arxiv.org/abs/2412.01743.

Paper now out in PNAS! Our colloidal whole-cell simulations + in vivo 3D particle tracking reveal how macromolecular interactions and confinement determine dynamics/localization in E. coli. Congrats Alp Mehmet Sunol & Diana Valverde Mendez!  pnas.org/doi/10.1073/pn…

Excited to present NEW WORK at APS! The ZiaLab is headed to the 2025 American Physical Society Global Summit! Catch Vishal Sivasankar as he presents our latest work on whole-cell modeling of Escherichia coli. Don’t miss it! #APSMarch #APSSummit25

Excited to share new work now out in Nature Communications Biology! We use computational modeling to show how E. coli preloads its ribosomes to speed codon recognition testing & protein synthesis for faster growth. Check out the paper (open access) at doi.org/10.1038/s42003….

Excited to present our work on whole-cell modeling of E. coli and ribogenesis in at the American Chemical Society Fall 2025 Meeting! Great work from ZiaLab members Vishal Sivasankar, Jen Hofmann and Theo Yang. Come check it out at the Westin Potomac Salon 3, Monday 08/18 at 8:00AM!

Excited to share new research helping explain why synthetic minimal cell JCVI Syn3A's nucleoid is cell spanning. Great work by Zia Lab members Gesse Roure and Vishal Sivasankar! Check it out at the 5th Minimal Cell Workshop on October 3 at 8 am ET.(jcvi.org/events/minimal…).