Die Studie als Zusammenfassung jetzt veröffentlicht: Vor Daratumumab lag die Leistungsfähigkeit im SF-36 ≈ 30 (Alltag stark eingeschränkt). Nach Daratumumab stieg sie bei 6 von 10 Pat. auf fast 80 – vergleichbar mit weitgehend normaler Alltagsbelastung. frontiersin.org/journals/medic…

Interaction of HSV1 with nAChRs provides novel insights into a potential mechanism of action of HSV and its potential role in Alzheimer’s disease. nature.com/articles/s4429…

From Hungary "we report for the first time the activation of P2X7 receptors following SARS-CoV-2 infection is involved in the induction of anxiety & mood alterations through inflammatory pathways" sciencedirect.com/science/articl… Image from Science for ME update #NeuroPASC #LongCovid

Zurück von Capri: 3 Vorträge, PAIS-Care Berlin, Leitlinienarbeit, volle Praxis. Was mich fordert, ist nicht die Arbeit – sondern das System, das #MECFS-Betroffene strukturell übersieht -und mit seinen Fehlleitungen schädigt. Deshalb: Aufklären. Verändern. #PEMistnichtverhandelbar

Targeting P2X7 mitigates neurobehavioural alterations in a mouse model of post-acute sequelae of SARS-CoV-2 infection sciencedirect.com/science/articl…

onlinelibrary.wiley.com/doi/10.1111/sj…

This case report indicates that post-COVID-19 dizziness can be associated with a patulous eustachian tube (PET), & in that case, it can be successfully treated by placement of a ventilation tube.

More than 90% of RRMS patients given vidofludimus calcium in a clinical trial were free of confirmed disability worsening after three years. buff.ly/n3xB1NY #MultipleSclerosis #MSTreatment #MSResearch #MSNews

Mount Sinai researchers show that SARS-CoV-2 protein Nsp14 binds Tollip to drive inflammation while degrading interferon receptors, blocking key antiviral defenses and tilting the immune balance toward viral survival. journals.asm.org/doi/10.1128/mb…

LOLA (2 amino acids) as a potential treatment for BOTH long covid and mecfs. 🔔The paper lays out the “why” and “what” of the expected effects.

Professor Ron Davis, Stanford University: “If you get chronic fatigue syndrome or #MECFS, your life as you know it’s over. That is really sad, because it hits people at the prime of their life.” #MEAwarenessHour

Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) -a clinical pilot study. frontiersin.org/journals/medic…

A new review with Resia Pretorius on two more imaging methods for measuring effects of #fibrinaloid #microclots on the #microcirculation and endothelial damage. #TeamClots #pwLC #pwME preprints.org/manuscript/202…. Much pricier than #nailfold #capillaroscopy but impactful.

Hamburger Anwältin kämpft für ME/CFS-Patienten: „Mauer aus Ignoranz“ 1/2

Liebe Sarah Buckel, du bist Teil unseres Aufklärungsvideos, welches vor 2 Tagen die 1000 Schüler*innen der Kant-Schule Falkensee gesehen haben:

Long-COVID bei Kleinkindern: Viel häufiger als bislang angenommen? Demnach zeigten 14% der Säuglinge und Kleinkinder sowie 15% der Vorschulkinder in der untersuchten Kohorte Beschwerden, die mit Long-COVID vereinbar waren deutsch.medscape.com/artikelansicht…

Association and Interaction of Epstein–Barr Virus with SARS-CoV-2 Infection—A Review 🔥The thickening long Covid-EBV plot, interesting! ➡️The Epstein-Barr virus (EBV), a double-stranded DNA virus in the herpes family, infects 90% of the global population and is linked to

Persistence of Infectious Form of SARSCoV2 After Protease Inhibitor Treatment of Permissive Cells.(COVID19) Rx with nirmatrelvir, 3CL protease inhibitor;drug resistance, reinfection,lack of adequate immune responses- viral rebound, in 20% of treated cases. academic.oup.com/jid/article/23…

Monoclonal Antibodies in Long COVID Pemgarda > Sipavibart in neutralizing SARS-CoV-2 with greater potency due to enhanced binding to conserved spike regions and increased affinity - even against immune-evasive variants - suggesting broader and more durable activity. 🧵

Gericht gibt Klage auf GdB 50 wegen Post-COVID (PCS) statt. Laut Gutachter liege eine organisch bedingte Folgeerkrankung von C19 vor. Am ehesten sei PCS mit ME/CFS vergleichbar. Die GdB-Beurteilung müsse analog funktioneller Auswirkungen erfolgen. datev-magazin.de/nachrichten-st…