I'm excited to announce that the "Miga Lab" will officially have a home in the Biomolecular Engineering (BME) Department at UCSC this Fall & I am honored to join the UCSC Genomics Institute as an Associate Director. migalab.com. @UCSC_BSOE UC Santa Cruz Genomics Institute 1/4

From telomere to telomere: the transcriptional and epigenetic state of human repeat elements biorxiv.org/content/10.110…

What happens when DNA-loop-extruding SMCs collide with one another in a living cell? Our article on SMC complexes bypassing one another in vivo is out NatureStructMolBiol, in a wonderful collaboration with Xindan Wang, Leonid Mirny, Warren Ren and @Xciencepig. rdcu.be/cpVDg

In the latest issue! Meiotic recombination mirrors patterns of germline replication in mice and humans dlvr.it/S5DjRz

The chair is really cool, too. 😉

Interested in obtaining a PhD in microbiology and molecular genetics? Apply to the DukeMGM PhD program by December 1!

New in Science: Researchers introduce “Giraffe,” an open-source short-read mapping algorithm for human pangenomes that can map sequencing reads to thousands of human genomes at a speed similar to that of standard methods. fcld.ly/sqrlu0i

Sad to hear of the passing of Haig Kazazian, a giant in the field of human genetics. After identifying a LINE1 insertion causing hemophilia, his lab trail-blazed 30+ yrs of key discoveries on human transposons. An amazing career he narrated here: annualreviews.org/doi/abs/10.114…

"...it was a big revelation that it wasn’t just a bunch of genes strung out along the chromosome, that there were these big deserts in between genes." #SN100 sciencenews.org/century/dna-ge…

Students/postdocs: This is the cheatsheet for how to manage/interact with your PI. PIs: It's turtles all the way up.

🎉BIG NEWS! 🎉 We've FULLY SEQUENCED the HUMAN GENOME! 🧬 This breakthrough achievement could lead to HUGE advances in medicine and research. Thanks to UCSC's Karen Miga & National Human Genome Research Institute 's Adam Phillippy for leading the #T2T team through this monumental effort! news.ucsc.edu/2022/03/t2t-ge…

Centromeres have been difficult to analyze because they comprise highly repeated DNA. Long-read sequencing has made it possible to study their structure and evolution. Read more in this Perspective by Steven Henikoff Fred Hutchinson Cancer Center Genome Research ow.ly/FSKI30sg79G #T2T

A fully sequenced human genome was announced more than 20 years ago. Science Magazine, Genome Research, and others report on the efforts of the Telomere-to-Telomere (#T2T) Consortium to complete a comprehensive human reference genome. ow.ly/9S5130sg7eK

Excited to announce our publication on repeats (& their transcriptional and epigenetic patterns) in a truly complete human genome, led by Savannah Hoyt with the incredible help of Gabby Hartley Patrick G.S. Grady, Ph.D. (he/him), and are co-authors on several of the other papers in this issue!

Celebrating Mendel, McClintock, and Darlington: On end-to-end chromosome fusions and nested chromosome fusions - Martin A Lysak CEITEC Masaryk University #PlantSci buff.ly/3Ezgl7W

Just received NOA for renewal of our human centromere R01 grant. We are extremely grateful to NIGMS, U.S. taxpayers, and study section reviewers for their support of our research. 🧬 🔬🥼

We are looking for a #TenureTrack #AssistantProfessor who will develop an outstanding research program to address a significant biological or human disease-related questions: ow.ly/vqGL50JYF8n DukeMGM #Genome #genomics #epigenomics

Glad to see our review on Chromosomal Instability (CIN) in cancer out today as part of a special issue guest edited by Stefano Santaguida #ChromosomeResearch It was a pleasure to contribute! Mayo Clinic Urology Mayo Clinic link.springer.com/article/10.100…

Creating Outstanding Opportunities for Postdoctoral Trainees (CO-OPT) in Genomic Technologies invites prospective postdoctoral fellows to visit Duke University. Present your research, explore research opportunities in DukeCAGT, & network with new colleagues! cagt.pratt.duke.edu/postdocs/coopt