Molecular, clinical, and therapeutic determinants of outcome in NPM1-mutated AML ashpublications.org/blood/article-… Key takeaways Adverse risk CG, WT1, DNMT3A, FLT3ITD were associated with high rate of MRD+ by PCR & ⬆️ relapses In spite of high risk molecular features, MRD- overcome bad

Absence of PNH-clones in DDX41mutant-GPS aids in their distinction from acquired bone marrow failure syndromes ... sciencedirect.com/science/articl… yael kusne MD PhD Tim Chlon Talha Badar Mayo Clinic Comprehensive Cancer Center #DDX41 #Bonemarrowfailure

Cerebrospinal fluid distribution and pharmacokinetics of ponatinib in Ph+ acute lymphoblastic leukemia ashpublications.org/blood/article-… Case series of 16 Ph+ ALL, showed sub-optimal CSF concentration of ponatinib. #Leusm #ALL

Excited to share our review in Blood Journal !! Mark Litzow #Dr_Selina_Luger #ALL #leusm #immunotherapy Incorporation of immunotherapy into frontline treatment for adults with B-cell precursor acute lymphoblastic leukemia. ashpublications.org/blood/article-…