Dr Amol Akhade(@SuyogCancer) 's Twitter Profileg
Dr Amol Akhade

@SuyogCancer

Oncology care , to give or not to give chemo , data analysis , oncology pharamocovigilance , enthusiastic critic, twitts are not twists

ID:1135941148378247168

linkhttp://suyogcancerclincs.com calendar_today04-06-2019 16:07:29

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Dr Amol Akhade(@SuyogCancer) 's Twitter Profile Photo

Today Voted for Strong Nation and Strong leadership.
๐Ÿ’ชStrong leadership = Strong Nation ๐Ÿ‡ฎ๐Ÿ‡ณ .
Captain Matters .

Today Voted for Strong Nation and Strong leadership. ๐Ÿ’ชStrong leadership = Strong Nation ๐Ÿ‡ฎ๐Ÿ‡ณ . Captain Matters .
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The waiting time to see qualified oncologist in India ๐Ÿ‡ฎ๐Ÿ‡ณ varies from few hours ( for all major cities ) to may be a day or two for any remote corner of the country .Access to oncologist is not a issue for us .
Cost of therapy and affordable treatment is main issue .

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USFDA rejects another China ๐Ÿ‡จ๐Ÿ‡ณ Made IO inspite of wide separation of OS curves . Camrelizumb plus Rivoceranib combination for Advanced HCC is rejected by U.S. FDA . Free HOME Run for Atezolizumab plus bev ? ๐Ÿค” Tanios Bekaii-Saab, MD Axel Grothey

USFDA rejects another China ๐Ÿ‡จ๐Ÿ‡ณ Made IO inspite of wide separation of OS curves . Camrelizumb plus Rivoceranib combination for Advanced HCC is rejected by @US_FDA . Free HOME Run for Atezolizumab plus bev ? ๐Ÿค” @GIcancerDoc @agrothey
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Tarlatamab. Anti -DLL3 BiTE got accelerated approval for extensive stage SCLC . Based upon Delphi-301 study , phase 2 .
Approved dose is 1 mg on cycle 1 day 1 and 10 mg on cycle 1 day 8 and 15 and then every 2 weekly .

Time to BiTE SCLC U.S. FDA IASLC

Tarlatamab. Anti -DLL3 BiTE got accelerated approval for extensive stage SCLC . Based upon Delphi-301 study , phase 2 . Approved dose is 1 mg on cycle 1 day 1 and 10 mg on cycle 1 day 8 and 15 and then every 2 weekly . Time to BiTE SCLC #LCSM @US_FDA @IASLC
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Checkmate 77T. Perioperative Nivolumab in early stage resectable NSCLC. EFS benifit as per Stage and PDL1 expression. Subsequent therapies for both arms . How much additional benifit this gives over only neo adjuvant nivo . We don't know. NEJM

Checkmate 77T. Perioperative Nivolumab in early stage resectable NSCLC. EFS benifit as per Stage and PDL1 expression. Subsequent therapies for both arms . How much additional benifit this gives over only neo adjuvant nivo . We don't know. @NEJM
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The eternal question. Can we give olaparib and abemaciclib both for adjuvant treatment in ER postive Her2 negative EBC with Brca postive- if u can manage toxicity, u can discuss- data for OS for this subset is not yet matured ESMO - Eur. Oncology OncoAlert Erika Hamilton, MD Oncology Brothers

The eternal question. Can we give olaparib and abemaciclib both for adjuvant treatment in ER postive Her2 negative EBC with Brca postive- if u can manage toxicity, u can discuss- data for OS for this subset is not yet matured @myESMO @OncoAlert @ErikaHamilton9 @OncBrothers
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Personalized medicine in early breast cancer- where we are and where we are heading-
Do u think ctDNA based monitoring will be realistic In EBC in near future? Some data from monarchE to support . Erika Hamilton, MD Dr Sarah Sammons Sara Tolaney ESMO - Eur. Oncology

Personalized medicine in early breast cancer- where we are and where we are heading- Do u think ctDNA based monitoring will be realistic In EBC in near future? Some data from monarchE to support . @ErikaHamilton9 @drsarahsam @stolaney1 @myESMO #esmobreast24
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Important points about Her2 low and ultra low reporting in clinical practice. Useful for clinical practice especially , for pathologist and oncologist ESMO - Eur. Oncology

Important points about Her2 low and ultra low reporting in clinical practice. Useful for clinical practice especially , for pathologist and oncologist @myESMO #esmobreast24
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Sotorasib dosing issue is getting attention and rightly so . 240 mg is the right dose and @usfda should remove the approval for higher dose ( 960 mg ) Vinay Prasad MD MPH

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Diminishing role of surgery in pleural mesothelioma? MARS2, phase 3 RCT has shown that extended pleurectomy decortication was associated with worse survial to 2 years and more serious adverse events for individuals with resectable pleural mesothelioma, compared to

Diminishing role of surgery in pleural mesothelioma? MARS2, phase 3 RCT has shown that extended pleurectomy decortication was associated with worse survial to 2 years and more serious adverse events for individuals with resectable pleural mesothelioma, compared to
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One more trial to show that u can not give IO drugs along with Chemoradiation in stage IIIB NSCLC . Checkmate 73L . Concurrent Nivo plus cCRT followed by Nivo plus IPI or Nivo alone vs Pacific arm ( cCRT followed by Durva ) failed to show PFS benifit. Press release.

One more trial to show that u can not give IO drugs along with Chemoradiation in stage IIIB NSCLC . Checkmate 73L . Concurrent Nivo plus cCRT followed by Nivo plus IPI or Nivo alone vs Pacific arm ( cCRT followed by Durva ) failed to show PFS benifit. Press release.
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