✅ Central line salvage is safe and effective in #children with #intestinalfailure, with a 91.6% success rate. #CLABSI 🚫 Fungal infections are less likely to be salvaged. No increased complications at 30 days. #openaccess #cme onlinelibrary.wiley.com/doi/10.1002/jp…

Study compares #Vedolizumab (VDZ) and #Ustekinumab (UST) for #pediatric UC refractory to anti-TNF therapy. Both show similar effectiveness at 6 months, with 28.3% (VDZ) and 25.8% (UST) achieving corticosteroid-free clinical remission. #IBD #CME onlinelibrary.wiley.com/doi/10.1002/jp…

Study assesses a whole-food smoothie as exclusive enteral nutrition #EEN for #pediatric #Crohnsdisease. Over 4 weeks, 80% achieved remission, with significant reductions in inflammation and increased #microbiome diversity. #IBD #openaccess onlinelibrary.wiley.com/doi/10.1002/jp…

#Children with #shortbowelsyndrome have higher risk for eosinophilic gastrointestinal diseases #EGID. 10% had #EoE 4.9% eosinophilic gastritis 4.9% eosinophilic enteritis #Allergy or atopy increased the likelihood of EGIDs. onlinelibrary.wiley.com/doi/10.1002/jp…

📢Check our August issue ‼️ 💥Featured article: EASL position paper on clinical follow-up after HCV cure🔗bit.ly/3Va2uh2 Full issue here👉bit.ly/36khmDF #LiverTwitter Paolo Angeli EASL Education EASLnews

The IBD landscape is getting intense with so many exciting trials! 📈 #IBD cheatsheets just updated in light of recent publications 😃 ibd-eii.com/ibdcheatsheet

Here is my full review of the most impactful papers in IBD so far this year SEQUENCE study compares Risankizumab (RIS) and Ustekinumab in people with Crohn's Disease who have lost response to an anti-TNT medication (IFX or ADA) What is the significance of the picture?

A study on #pediatric #Crohnsdisease reveals that small bowel dilation >28mm on MRE and prior antibiotic exposure increase the risk of surgical resection. 🌟 Identifying these factors may guide early #surgery decisions. #IBD onlinelibrary.wiley.com/doi/10.1002/jp…

Rescue therapies for acute severe ulcerative colitis ✅tofacitinib, accelerated infliximab, IFX, tacrolimus ⬇️ short term colectomy rate ✅IFX10 & cyclosporine ⬇️ colectomy ❌ ustekinumab & adalimumab do not reduce colectomy #MedTwitter #GITwitter #IBD academic.oup.com/ecco-jcc/advan…

A study on #dupilumab in adolescents with #EoE showed 89% of inflammatory and 100% of fibrostenotic cases achieved histological response within 17-19 weeks. Dupilumab was also effective for non-EoE #EGID with longer therapy. onlinelibrary.wiley.com/doi/10.1002/jp…

In a Phase 2 study, sofosbuvir-velpatasvir achieved a 92% cure rate for chronic #HepC in #children aged 3-17. SVR12 rates were 95% (12-17 yrs), 93% (6-11 yrs), and 83% (3-5 yrs). The treatment was well tolerated. #hepatitisC #Pediatrics onlinelibrary.wiley.com/doi/10.1002/jp…

A vibrating capsule improves #constipation and quality of life even in the most severe cases of chronic constipation. #MedTwitter #GITwitter #motility onlinelibrary.wiley.com/doi/10.1111/ap…

Out-of-pocket expenses for managing cow's milk protein allergy in young #children can reach up to 15% of a family's income. Older children and those with additional food #allergies report lower quality of life. #Pediatrics onlinelibrary.wiley.com/doi/10.1002/jp…

Dual biological therapy shows promise for treating children with severe, refractory #IBD. ✅ 45% achieved clinical remission within 12 months, offering a potential alternative for those failing previous treatments. #Pediatrics #Gastroenterology onlinelibrary.wiley.com/doi/10.1002/jp…

🌟 ESPGHAN #Nutrition Committee position paper🌟 Infant formulas for functional GI disorders like colic, constipation, and regurgitation are often used but lack strong evidence for effectiveness. #Pediatrics onlinelibrary.wiley.com/doi/10.1002/jp…

Pediatric #IBD patients with acute #pancreatitis have a milder clinical course than non-IBD peers. IBD-associated arthritis is a key risk factor, while meds surprisingly are not. #Pediatrics #openaccess onlinelibrary.wiley.com/doi/10.1002/jp…

📢 New article on this #JCAGJeudi 📰 Practical guidance for managing patients with moderate-to-severe ulcerative colitis using small molecule therapies ✍️by Vipul Jairath, Waqqas Afif, Brian Bressler, Janet E Pope, Daniel Selchen, and others 🔗academic.oup.com/jcag/article/7…

How do #microplastics, a rising pollutant of the modern environment, impact intestinal inflammation and #IBD risk? We had a great time working on a review with Maria Manuela Estevinho Kristine Allin Jean-Frederic Colombel Alvise Vianello BUILDaau & colleagues STOTEN (1/6)

🚨Button #battery ingestions ➡️ severe injuries in kids 🔵 New Energizer “color alert technology” dyes kids mouth BLUE if swallowed 🆘 If your 👶🏽 👧🏽👦🏽 mouth is blue ➡️ SEEK emergency care ASAP! tinyurl.com/ycy2za4f Dr. Free N. Hess, PediMom American Academy of Pediatrics US Consumer Product Safety Commission Camille Bonta NASPGHAN

Dr. Jennifer Hadam WVU GI Fellowship provides an overview of Emerging Therapies in IBD ! IL-23’s are making a splash 💦, Position early! S1P’s have a useful role in UC remission JAKi’s are rapid in action And MORE to come ! Pennsylvania Society of Gastroenterology (PSG) #PSG2024