We are very excited to see our latest paper online in nature. Great effort by Sungchul Kim, @l_loeff and the rest of the team. The paper sheds light on how bacteria memorize enemies using the #CRISPR #Cas1-Cas2 complex. disq.us/t/3maq49d

Cas1/2 can anneal ssDNA and gets spacers from diverse, partially duplexed DNAs. DnaQ exonucleases then trim spacer to appropriate size for integration, with the PAM-proximal end protected to ensure proper orientation. A great read on biorxiv last year and nice to see in print!

Congrats to our BN colleagues at Joo_Lab and Stan Brouns for the nice Crspr work that appeared today in nature

Check out TU Delft news about our recent #CRISPR #Cas1-Cas2 study. Monitoring the development of a tumour using the memory of bacteria tudelft.nl/en/2020/tnw/mo…

Thanks Rob!! 👍🏻😁 I hope to see you soon!😊

Many surprises on SMC proteins in this nature #CDlab paper: nature.com/articles/s4158… : - DNA loops can mutually exchange size. - Condensins can pass one another! - to form totally new type of ‘Z-loops' - that can fill DNA gaps - and can form a symmetric DNA-pulling dimer motor

Congratulations Eugene and Cees!! Fantastic!! 👏👍🏻🎉😁

I have much experience for RNA extraction and RT-PCR. I would help the test if samples are tranferred as TRIZOL-treated. BN may be able to use ML-2 lab that has been designed for bacteriophage research, if it needs. Anyway, the more tests the better.

My friends in SNU published very easy protocol for the test of COVID-19 virus by RT-PCR. It seems realistic in our labs in BN, if the materials are enoughly provided. researchgate.net/publication/33…

Many thanks! @dhingrayukti1 Dipa Sashital and The CRISPR Journal !

Today we are recording a nature Webcast on the latest research done in the field of #SingleMolecule #Proteomics Please register and join us May 28th to find out more about this exciting field! workcast.com/register?cpak=…

This is another tremendously important single-molecule work about the molecule function of #CRISPR #Cas1_Cas2. Congratulations, Ailong Ke's Lab at Yale MB&B and Jagat Budhathoki!👍🏻 nature.com/articles/s4159…

Check out our Nature Communications paper about the structure of DmpR, a bacterial phenol-binding transactivator protein. Thanks so much, Dr. Eui-jeon Woo and Dr. Kwang-hyun Park in KRIBB for this long-lasting collaboration. nature.com/articles/s4146…

Trying to blow out the Corona ball by homerun hitting with my amazing baseball bat. 😁 Baseball is social distancing sports. 🤗

independentsciencenews.org/commentaries/a…

BREAKING NEWS: The 2021 #NobelPrize in Physiology or Medicine has been awarded jointly to David Julius and Ardem Patapoutian “for their discoveries of receptors for temperature and touch.”

Slowly read the latest GlycoRNA paper (biorxiv.org/content/10.110…) and the original findings (doi.org/10.1016/j.cell…). Do you then think GlycoRNA, as originally described, is:

Here is our new bioRxiv preprint that studied about critical issues for glycoRNA purification. #glycoRNA #glycotime #RNA_purification N-glycosylated molecules act as a co-precipitant in RNA purification biorxiv.org/content/10.110…

If you have been working or plan to work on #glycoRNA, please spend some #glycotime through this thread, because it is worthwhile knowing the risk you may encounter.

The jury has reached its verdict! Kudos to very well executed science all round, a subtle and difficult area.