Happy to share our new paper in Nature Communications. We demonstrate super-multicolor Tetbow labeling of neurons with 7 fluorescent proteins and fully automated reconstruction of neurites. Big congrats to Marcus Leiwe, Satoshi Fujimoto, and Toshikazu Baba. nature.com/articles/s4146… (1/10)

All the lines are striking - the sharp rise in China such that per capita emissions higher than Europe, the dramatic decline of US (but still the highest), how low India remains despite recent increases.

Academic job stability (without tenure)

neuroscientists now routinely collect cell-count data over 100+ brain regions per animal (eg elifesciences.org/articles/59272). But the experiments are hard, so <10 animals per group. Bad regime for stats! We developed a bayesian method which outperforms t-tests: biorxiv.org/content/10.110…

Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes: Neuron cell.com/neuron/fulltex…

The role of a plant peptide in coordinating developmental and immune response signalling. elifesciences.org/articles/87912…

Our special August issue focused on glia is now live! nature.com/neuro/volumes/…

At least one-quarter of people who have severe brain injuries and cannot respond physically to commands are actually conscious, according to the first international study of its kind. go.nature.com/4fPiU7I

New preprint: We have developed an integrated pipeline to i) image gastruloids in toto with dual-view 2-photon🔬, ii) quantitatify cell and tissue-scale patterns of gene expression and morphometric features, iii) interact with the data in napari🔬. biorxiv.org/content/10.110…

What if you could deliver molecular tools directly into oocytes without microinjection? In our new paper, online today Development (doi.org/10.1242/dev.20…), we introduce VitelloTag, a new cargo delivery tool to enable injection-free genome editing. 👇Read on for a short 🧵

Another stunner from Patrik Ernfors on the neural circuitry behind how morphine relieves pain science.org/doi/10.1126/sc…

Online Now! Inflammation-induced epigenetic imprinting regulates intestinal stem cells dlvr.it/TCmw37 #stemcells

Analyzing embryo dormancy at single-cell resolution reveals dynamic transcriptional responses and activation of integrin-Yap/Taz prosurvival signaling dlvr.it/TCt1LF

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye! The dye is tartrazine, used in Doritos! science.org/doi/10.1126/sc…

Dozens of labs around the world are striving to grow models of human embryos to study development, fertility and therapies. They are entering uncharted ethical territory. go.nature.com/3ZhjpSt

Our newest publication is out! We demonstrate that activation of the muscle to brain axis promotes synaptic remodeling in the CNS, and improves neurocognitive behavior in the 5xFAD model of AB plaques link.springer.com/article/10.100…

Excited to share our new bioRxiv preprint: Isotonic and minimally invasive optical clearing media for live cell imaging ex vivo and in vivo.  biorxiv.org/cgi/content/sh…

VitelloTag: a tool for high-throughput cargo delivery into oocytes Read this #DevSIDiversity Techniques & Resources Article by nat clarke (MIT Biology), Akshay Kane, Margherita Perillo, Christopher Lowe & @ZakSwartz (Marine Biological Laboratory (MBL)): journals.biologists.com/dev/article/15…

This is apparently a protein-protein interaction diagram... Published in 2024 by Elsevier's Journal of Agriculture and Food Research. doi.org/10.1016/j.jafr…

Our 5 cents on disease-associated oligodendroglia Trends in Immunology sciencedirect.com/science/articl…