The ASCI leadership wants to hear from physician-scientists across the career span! Brief, one-page survey: buff.ly/3fZ9sVi Sohail Tavazoie Ben Humphreys Anna Greka

I present to you Dr. Nneoma Adaku !! Rockefeller University Tri-I MD-PhD @theemdphd

The amazing Tri-I MD-PhD student Lisa Earnest-Noble's paper is out showing that two so called 'synonymous' isoleucyl tRNAs opposingly regulate breast cancer & metastasis by driving distinct gene regulatory programs. Rockefeller University also thx to Hani Goodarzi nature.com/articles/s4301…

I am also going to the Forbidden Elephant site under @sohailtavazoie

Very happy to present our recent work examining how nutrient limitation shapes the cancer genome! science.org/doi/10.1126/sc… Thank you to Sohail Tavazoie, Saeed Tavazoie, and all others who made this work possible

How does Codon bias emerge? Dennis Hsu shows: limiting arginine causes arginine codon switching mutations in cancer: Low Arg aa-> reduced Arg tRNA->ribosome pausing->proteomic shift->DNA evolution. big thx to Saeed Tavazoie @columbia @rockefeller science.org/doi/10.1126/sc…

Discovery of Prognostic cancer modules !

Incredibly proud of our lab's physician-scientist graduates Maria Passarelli, MD, PhD and Kristina Navrazhina, who matched in pediatrics Boston Children's & dermatology Mount Sinai Health System, respectively!! The future is in very good hands! Rockefeller University Tri-I MD-PhD Weill Cornell Medicine

Fellow 2022 class inductee Katalin Kariko takes our National Academy of Medicine ceremony to the next level :O

Zhijian "James" Chen celebrity sighting at the National Academy of Medicine induction ceremony. @UTSWNews Rockefeller University

Transfer RNAs (tRNAs) are increasingly found to play dynamic and critical regulatory roles in cancer progression. Alexandra Pinzaru's review describes this exciting area of research: nature.com/articles/s4156…

Congrats to amazing Alon Millet and Jose Ledo on discovering an exhausted-like microglial population that accumulates in aged and APOE4 Everyday Health brains of humans and mice and is defective in amyloid clearance Rockefeller University cell.com/immunity/fullt…

Discovery of terminally inflammatory microglia (TIM), akin to exhausted T cells, in the brain of people with advanced age, dementia,⬆️w/APOE4. In parallel to the mouse experimental model cell.com/immunity/fullt… Rockefeller University Sohail Tavazoie Alon Millet

Excited that our creatine transporter inhibitor therapy RGX-202 is advancing to international randomized trials with Merck KGaA as anti-metastatic therapy of @colorectalcancer based on lab findings of Jiamin Loo, Norihiro of RU & Isabel Kurth, Masoud Tavazoie....Inspirna

How breast cancer cells hijack sensory neurons and a path to possible treatment nature.com/articles/s4158… Sohail Tavazoie Veena Padmanaban nature.com/articles/d4158… nature Heidi Ledford

What a brilliant, bold and inspiring choice to head this storied institution Dana-Farber !!

The greatest story of fearless scientific discovery by two of the most creative, supportive, and kind scientists on the planet !!