Brad Loncar Regardless of whether one agrees with your statement above, the FDA is plainly functioning. Not so long ago, some people on my X stream asserted that the FDA was doomed.

That's an interesting thought no? Cc: @Ali

The US VP tweeting about the "reproducibility crisis" CRISIS more like it-wouldn't have been on my Bingo card for 2025 a few years ago!

That's a wonderful thread on Bortezomin/Velcade development history by someone who lived it!

By how much would a quarter more us patients increase clincial trial costs- surely the US patients are most expensive with everything healthcare related super expensive!

$RGLS / $NVS July 2024: First contact 1/10: Met at JPM 4/4: Offered $3 + $1.5 CVR 4/16: Offered $3.5 + $3.5 CVR 4/20: Offered $6 + $6 CVR 4/23: Offered $6.5 + $6.5 CVR 4/27: Offered $6 + $6 CVR 4/28: Best and final offer $7 + $7 CVR sec.gov/Archives/edgar…

Oh no - we thought Danon was a done deal for approval. Huge blow to Rocket with potential read through to all AAV9 programs? Will there be a path forward with a different immuno-suppressive agent? $RCKT -60% Rocket Pharmaceuticals Provides Update on Phase 2 Clinical Trial of

Yeah I saw this going up and up for as while but what's going on here?

High dose AAV is risky haven't we learnrned that over the past decade plus!

Same way I feel we have established that injecting stemcells (without some extra secret souce at least) just won't magical cure diseases yet it geht's tried over an over...

Do you guys also get the same commercial all over and over again like it's groundhog Day... Until you block the weirdos and their strange promotions... Funny that this is a running business and all

Astra's success from the "Sick man of Pharma" in 2013 to hitting the improbable forecasts in their takeover defense against Pfizer to their remarkable R&D success has been simply stunning- Soriots Astra or Lechleitners Lilly who would you rate higher 2013-2025?

Grok in the replies sees shoplifting happening here -hopefully they don't roll it out for crime video analysis too soon!

That's wild😭

$ITOS iTeos Therapeutics Announces Its Intention to Wind Down Operations. 👏

That's funny X because I dreamt that Glass wouldn't do the right thing (not to proohetic) and then an internet movement shamed them into changing their advice!

That's one crazy fact if you pause a sec to think about it!

Seems like I missed a lot today $REGN $SNY drop due to itepekimab? That's a drawdown you don't see often in large caps?

Such a list (of mice strain and their respective properties) would be sooo valuable and useful- why has no one written it yet!

$XBI — $BMY Anecdotal, but thought this comment interesting by Boerner about the new FDA: “We’re able to get in-person meetings for the first time in a number of years there.” .