Advancing global antibiotic research, development and access | Nature Medicine nature.com/articles/s4159…

BLAST research highlight: New structure/function studies reveal a sequence motif for purine binding in thousands of dCache_1 domains! nature.com/articles/s4146…

Tired of drawing biosynthetic pathways for your 15-module NRPS and PKS systems? Or are your eyes hurting from peering at stereocentres? Try visualising your biosynthetic diagrams automatically with RAIChU! jcheminf.biomedcentral.com/articles/10.11… github.com/BTheDragonMast…

Full article: The presence of differentiated C2C12 muscle cells enhances toxin production and growth by Clostridium perfringens type A strain ATCC3624 tandfonline.com/doi/full/10.10…

The presence of differentiated C2C12 muscle cells enhances toxin production and growth by Clostridium perfringens type A strain ATCC3624 pubmed.ncbi.nlm.nih.gov/39192628/

Structural and Functional Insights into the Delivery Systems of Bacillus and Clostridial Binary Toxins ncbi.nlm.nih.gov/pmc/articles/P…

Preparation and Application of Clostridium perfringens Alpha Toxin Nanobodies ncbi.nlm.nih.gov/pmc/articles/P…

Next week, the first webinar of the new ESCMID ESGCD webinar series for 2024-2025 will take place. Attendance is free. We hope to see many people there! Link to join: escmid-org.zoom.us/j/82758559493?… kerrie Davies Ed Kuijper Dave Roberts Joffrey van Prehn Ned. Vereniging voor Medische Microbiologie (NVMM)

Raffinocyclicin is a novel plasmid-encoded circular bacteriocin produced by Lactococcus raffinolactis with broad-broad-spectrum activity against many gram-positive food pathogens pubmed.ncbi.nlm.nih.gov/39189737/

Full article: Prevention and cure of murine C. difficile infection by a Lachnospiraceae strain tandfonline.com/doi/full/10.10…

A Clostridioides difficile endolysin modulates toxin secretion without cell lysis - nature.com/articles/s4200…

The role of extracellular structures in Clostridioides difficile biofilm formation sciencedirect.com/science/articl…

IL-13 protects from Clostridioides difficile colitis sciencedirect.com/science/articl…

Monoclonal antibody-mediated neutralization of Clostridioides difficile toxin does not diminish induction of the protective innate immune response to infection sciencedirect.com/science/articl…

Tip extension and simultaneous multiple fission in a filamentous Corynebacterium species - I am intrigued! pnas.org/doi/10.1073/pn…

A viral family tree gets a makeover! 🧬🦠🔍Our new study, out today in nature, reveals the Flaviviridae's hidden history. MRC-Uni of Glasgow Centre for Virus Research #virology nature.com/articles/s4158…

Why do we itch? Ask your immune system, and Dr. Sokol and colleagues. They provide a simple and elegant answer to this timeless question. Kudos to the authors on this fascinating discovery. nature.com/articles/s4158… Caroline Sokol MDPhD Harvard Medical School

Structures of the Mycobacterium tuberculosis efflux pump EfpA reveal the mechanisms of transport and inhibition | Nature Communications nature.com/articles/s4146…

Crestone Announces Positive Data From Phase 2 Clinical Trial of CRS3123 for C. Difficile Infections (CDI) dlvr.it/TCsfDK #cdiff #cdi