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Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling go.nature.com/2NVPf03

nature.com/articles/s4159…

Mind blowing stuff! Transcriptional recording by CRISPR spacer acquisition from RNA disq.us/t/36wfi2s

#ERCC Flagship paper from Srimeenakshi Srinivasan and colleagues - Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation Cell bit.ly/2IoQbJS

"RNA-Seq: the teenage years" Fig1 short-read, long-read and directRNA-seq technologies and workflows. Illumina PacBio Oxford Nanopore (sorry Ion Torrent & @MGI_BGI but we did not have space) rdcu.be/bLGeN Nature Reviews Genetics

Pipeline release! nf-core/smrnaseq v1.0.0(A small-RNA sequencing analysis pipeline. ) See the changelog:github.com/nf-core/smrnas…

Erythropoietic miR-486-5p and miR-451a depletion from whole blood-derived small RNA sequencing libraries dlvr.it/RFx4Hc

science.sciencemag.org/content/366/64…

We are looking for a PhD student to join the group of Intestinal immune regulation!

If you work with microRNAs in blood, please take a look at our recent paper: academic.oup.com/nargab/article…

The ABO blood group locus and a chromosome 3 gene cluster associate with SARS-CoV-2 respiratory failure in an Italian-Spanish genome-wide association analysis medrxiv.org/cgi/content/sh… #medRxiv

Towards a consensus microRNA signature of primary and metastatic colorectal cancer biorxiv.org/content/10.110…

Check out our new study in medRxiv: Genome-wide analysis of 944,133 individuals provides insights into the etiology of hemorrhoidal disease; first 102 risk loci for this trait! medrxiv.org/content/10.110…

#PhDposition available in my new lab CIC bioGUNE to study genetics & genomics of gastrointestinal diseases linkedin.com/jobs/view/2475…

just out in Gut Journal our GWAS of hemorrhoidal disease in 1 million people, new insight into pathogenetic mechanisms from 102 risk loci & their downstream functional annotation Andre Franke CIC bioGUNE Ikerbasque IKMB_BioInfoGen Karolinska Institutet Monash Science gut.bmj.com/content/early/…

STARsolo preprint is out on bioRxiv: biorxiv.org/content/10.110… STAR release 2.7.9a: github.com/alexdobin/STAR… The major new feature is quantification of multi-gene (multi-mapping) reads/UMIs, which are necessary to detect expression from overlapping genes and paralogs. 1/5

Iryna Tsvila of Ukraine’s National Guards Rapid Response Brigade. She was killed repelling a Russian armored assault outside Kyiv

Do you have genomic regions that are difficult to sequence and resolve with short read sequencing? Check out this paper by our very talented PhD student @Timotheus_Alex on high throughput bait based targeted sequencing on PacBio to resolve blood groups academic.oup.com/nargab/article…

#IBS #diverticulitis & #haemorrhoids are genetically linked, our Mendelian Randomization (MR) sheds light on their causal relationships (and rectifies previous literature) fantastic work by Simonas Juzenas with help from MR guru Serena Sanna & others pubmed.ncbi.nlm.nih.gov/37813565/

#miRNome of spatially distinct colonic epithelial cells in active and quiescent UC. Inciuraite et al. Juozas Kupčinskas Andre Franke academic.oup.com/ecco-jcc/advan…