Congratulations to @SimerPr27242963 for her latest publication.

For the first time we demonstrate a chaperone-like role of the external shell of bacterial microcompartments. Insights into the development of high temperature nano bioreactors.

Presented my work during scientific session on Research Scholar's Day at #INSTMohali

Fascinating ⬇️ how 'RNA' and 'protein' science travel the structure-disorder continuum: Proteins were assumed to be folded, but are increasingly recognized as disordered. RNA was assumed to be disordered, but is increasingly recognized as folded. doi.org/10.1073/pnas.2…

We are happy to share our recent article in Chemical Reviews showing how NMR Provides Unique Insight into the Functional Dynamics and Interactions of Intrinsically Disordered Proteins pubs.acs.org/doi/10.1021/ac…

Biomolecular condensates can both accelerate and suppress aggregation of α-synuclein dlvr.it/SP4kkz

Check out our new report on enhanced catalysis of nanocatalysts in confined microenvironment outfitted by liquid-liquid phase separation- now published in Chemical Communications-doi.org/10.1039/D2CC03… Silky bedi Gaurav Kumar Sabyasachi Rakshit INST Mohali

Four reasons why I think authorship on academic papers should be more like movie credits:

Disordered regions play a crucial role in the structure-function activity of well-structured bacterial microcompartments. Check out the case study done in our lab. tandfonline.com/doi/full/10.10…

Congratulations to Dr.Sharmistha Sinha for being featured as one of the 35 Young Vidushi in the Vigyan Vidushi - 75 Women Trailblazers of Science, a prestigious publication of Vigyan Prasar DSTIndia

Firsts are always special. My first oral presentation in MMT-2023 NIT Kurukshetra . I have explained the confinement of protein capped catalysts in liquid droplets and effect on their catalytic activity.

Biomolecular condensates can concentrate macromolecules and metabolites to boost or quench biochemical reaction. But what about gases? In the preprint below expertly led by Ankush Garg, we try to answer this question for oxygen. biorxiv.org/content/10.110…

LLPS can enhance catalytic reaction rates, but our latest study in collaboration with Sabyasachi Rakshit reveals a twist. At high substrate concentrations, phase transitions in droplets restrict movement, reducing reaction rates. doi.org/10.1039/D4NR01… Silky bedi S M Rose

In our latest collaborative research, we delved into the effects of increased substrate concentrations induced phase transition inside the catalytic condensates and its impact on rate of reaction S M Rose Sabyasachi Rakshit INST Mohali IISER Mohali

De-novo design of actively spinning and gyrating spherical micro-vesicles biorxiv.org/content/10.110… Check out our new bioRxiv article. Here, we harness the force generated by biomolecules to power the movement of giant vesicles, acting as wheels. IISER Mohali

Bile acids stirring the pot in Parkinson’s? Lithocholic acid (LCA) speeds up α-synuclein clumping by 75%, while deoxycholic acid (DCA) takes a 30% nudge. Together, they’re not exactly brain-friendly! Check out our recent findings at doi.org/10.1021/acsche… INST Mohali DSTIndia

Genes That Stick Together, Work Together! A molecular life lesson: teamwork and proximity shape success! In nature, who you’re next to matters! Check our latest publication to learn more! doi.org/10.1016/j.bbag… INST Mohali Silky bedi S M Rose

Silky just defended her thesis today! From BMC proteins to bioelectronics wizardry, she's been assembling more than just molecules. Go Dr. Silky! Dr Asifkhan Shanavas and Dr. Surajit Karmakar along with Dr. Kausik Chakraborty (IGIB) served the committee Silky bedi INST Mohali

Join the Sinha Lab at INST Mohali 🧬 Research on biomolecular self-assembly, synthetic biology, and disease mechanisms. 📩 Apply: sinhas[at]inst[dot]ac[dot]in 🔗 More info: inst.ac.in/scientist/24-s…; inst.ac.in/careers #PhDPosition #SyntheticBiology #Biophysics