New Receptor “Decoy” Drug Neutralizes COVID-19 Virus and Its Variants ://ms.spr.ly/6047eW78R

An effective tool developed by Genentech to evaluate the IVT efficiency of NCAA in peptidic library design and synthesis... Titled as "Evaluating Translational Efficiency of Noncanonical Amino Acids to Inform the Design of Druglike Peptide Libraries"pubs.acs.org/doi/full/10.10…

Engineered PROTAC-CID Systems for Mammalian Inducible Gene Regulation pubs.acs.org/doi/10.1021/ja…

Our latest paper is out at bioRxiv. Great work from Franco Faucher and collaboration with Alex Adibekian. biorxiv.org/content/10.110…

Paper just published. That was fast! Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows - Faucher - Israel Journal of Chemistry - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/ij…

Congrats to BC and YB on their recent paper on DEL selection of biased GPCR agonists! Big thanks to terrific collaborators Amal and Tao! #DELagonists #CIDselection #JACSau pubs.acs.org/doi/10.1021/ja…

Did you register yet to ABPP 2023??? 17-19/7/2023 Please RT! 🧪💥weizmann.ac.il/conferences/AB… #ABPP #Proteomics #Covalent #BestMeetingEver

Check it out! Laura Keller’s masterpiece of her thesis work is finally in print. Great work and just in time for her graduation. nature.com/articles/s4158…

Awesome paper from Jack Taunton’s lab ⁦UC San Francisco⁩ on direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes using chemoproteomics! nature.com/articles/s4155…

Check out our latest work targeting the malaria proteasome. Another outstanding collaboration with The Fidock Lab. Congrats to John Bennett and the other authors! pubs.acs.org/doi/10.1021/ac…

I'm delighted to release the first half of my new open-access online textbook in human population genetics: web.stanford.edu/group/pritchar…

A huge congrats to my graduate student Andy Heindel for publishing his work on developing PACCE for global quantification of protein-RNA binding activity in live cells. We thank our collaborators Markus Hafner NIAMS & Thurl Harris UVA Pharmacology. disq.us/t/4jhbf7b

Looking for a new covalent electrophile for serine and cysteine nucleophiles? Check out this great work by ⁦Jeyun Jo⁩ and ⁦Tulsi Upadhyay⁩ developing an oxadiazolone based probe for the S aureus serine hydrolase FphE. biorxiv.org/content/10.110…

After a lot of work by Sijie Wang to finish the project I started while at Genentech on sabbatical last year, we have finally posted the results to bioRxiv. biorxiv.org/content/10.110…

A great collaboration between Bogyo lab and Genentech. I had a lot of fun learning mRNA display and warhead encoding! Big thanks to all collaborators involved in this project! Emily C. Woods Jeyun Jo JiyunZhu Nikki Pedowitz Tulsi Upadhyay John Bennett

Busy week for Sijie Wang! His second paper in two days is out describing the use of phage display to identify covalent inhibitors of protein/protein interactions. Great work and collaboration. biorxiv.org/content/10.110…

Thanks Dan Nomura for highlighting our recent work!