#ASCO22 #PlenarySession summary 1. #DESTINYBreast04: TDXd in low HER2 mBC 2. #PARADIGM: Pan + mFOLFOX6 vs Bev + mFOLFOX6 in mCRC 3. #rEECur: Topotecan, cyclophos & HD ifos in Ewing #Sarcoma 4. #DETERMINATION: RVd +/- ASCT + Rev in myeloma #BCSM #CRCSM #GISM #MMSM OncoAlert 1/5

Very proud of our study published in NEJM. 100% clinical complete response with dostarlimab alone in mismatch repair-deficient locally advanced #RectalCancer. No radiation or surgery! ASCO #ASCO22 Memorial Sloan Kettering Cancer Center nejm.org/doi/full/10.10…

Delighted to work with Shyam Prabhakar Lab, sabine Tejpar, Joanito & many talented colleagues on our paper, using insights from single-cell & bulk -omics to propose an update to CMS classification of colorectal cancer, in Nature Genetics 1/ nature.com/articles/s4158…

What it looks like when a T cell DESTROYS a cancer cell 🤯 #MedTwitter x.com/Rainmaker1973/…

Prof. Toh Han Chong, APGCS Committee and Deputy Director, National Cancer Centre, Singapore, welcoming speech during the 1st day of APGCS 2022! #apgcs2022

#happeningnow 1st SingHealth Peritoneal Surface Oncology Conference in 🇸🇬!. Congrats to Ong Chin-Ann Johnny Jolene Wong Claramae Chia on the successful opening! #SPRinT Plenarytalk: Prof Med.Beate.Rau on setting up a comprehensive peritoneal centre 💥💥

New Research: The distinct clinical trajectory, metastatic sites, and immunobiology of microsatellite-instability-high cancers: Microsatellite-instability-high (MSI-H) cancers form a spectrum of solid organ tumors collectively known as Lynch… frontiersin.org/articles/10.33… #Genetics

The APGCS 2023 committee members welcome you all to attend the 10th Asia-Pacific Gastroenterology Cancer Summit happening on 18th & 19th August, 2023 in Singapore! Block Your Calendars and Save the Date! Shaheenah Dawood toh han chong Pierce Chow @sundar__ragha Shuting Han Iain Tan, NCCS/GIS/Duke-NUS/STCC

Shaheenah Dawood toh han chong Pierce Chow @sundar__ragha Shuting Han Iain Tan, NCCS/GIS/Duke-NUS/STCC

⚡️Truly an excellent discussion by Lizzy Smyth @#ESMO23. 💥 KEYNOTE 585 & MATTERHORN - adding immunotherapy as neoadjuvant therapy in locally advanced gastric and GEJ tumors. 🇩🇪 microbiome or the oncologists - why do Germans do FLOT better! 😁

Grateful for the opportunity to discuss important data at #ESMO2023 on the rapidly growing role of immunotherapy in gastrointestinal cancer. Understanding tumor biology is key. Chiara Cremolini Filippo Pietrantonio Lizzy Smyth Myriam Chalabi Sam Klempner Sara Lonardi Pamela Kunz, MD, FASCO

Fact, #gioncologists are cool. A great honour to be part of the global #GI #oncology community! Truly appreciative of our friends from afar coming to 🇸🇬! Thank you ESMO - Eur. Oncology #ESMOAsia23 #NCCSNCIS Shuting Han Raghav Sundar George Pentheroudakis @DucreuxMichel Robert Walsh

Arrived in #Singapore APGCS2025 to give an update on IO for MSI-H CRC and some hope for patients living with MSS CRC too. Judging by today’s UGI session/MDT debates with Raghav Sundar, Shaheenah Dawood et al, I’m looking forward to be challenged! Shuting Han Iain Tan, NCCS/GIS/Duke-NUS/STCC 🧐

Fantastic to meet exciting generation of clinical trialists-scientists + make new friends with 🌎🌍🌏 experts #ESMOASIA24 ESMO - Eur. Oncology Collaborative ideas across tumour types Evelyn Wong Shuting Han Ryan Huey, MD, MS Dr. Cathy Eng Pamela Kunz, MD, FASCO Herbert Loong, MBBS, FASCO Tom Powles John Haanen et al 🤝🤝

New research - Aspirin after completion of standard adjuvant therapy for colorectal cancer (ASCOLT): an international, multicentre, phase 3, randomised, double-blind, placebo-controlled trial thelancet.com/journals/langa… #GITwitter #OncTwitter #MedTwitter OncoAlert

Very proud of toh han chong John Chia Chee Kian and many others (across 11 countries and 66 sites) for bringing this trial to completion after >15 years of hard work and perseverance! A trial started in national cancer centre singapore 🇸🇬 just happy to be part of the story 🥳

At #ascogi 2025. So excited to listen to the Keynote by Pamela Kunz, MD, FASCO on inclusive medicine and science. Such an apt talk for today's world and changes. 😍

The March issue of The Lancet Gastroenterology & Hepatology is out now at thelancet.com/gastrohep! Content includes: alcohol & cancer risk, colorectal cancer, inflammatory bowel disease, appendicitis, MASLD, viral hepatitis + more... #GITwitter #LiverTwitter #MedTwitter

✅Successfully treated (& discharged!) the first solid cancer #celltherapy #TIL Iovance Biotherapeutics pt in #Asia #Singapore National Cancer Centre Singapore Thank you to all doctors, nurses, coordinators from #Haematology, #ICU, #InfectiousDisease #StemCell lab Singapore General Hospital (SGH) SingHealth - epitome of #teamwork!