New class of anti-inflammatories! Our latest work, published in Nature Communications, introduces new chemokine inhibiting proteins from ticks. doi.org/10.1038/s41467… Congratulation to PhD student Shankar Raj Devkota #StoneLab Monash Biomedicine Discovery Institute Pramod Aryal Payne Research Group Wanting Jiao CIPPS

I am excited to share my PhD. work published in Nature Communications.All about discovery, characterisation and enginneering of class A3 evasins inhibiting the inflammatory chemokines. nature.com/articles/s4146…

Tick evasin proteins block the inflammatory activity of mammalian chemokines. Sstructure-based modification of class A3 evasins alters their chemokine selectivity, suggesting these evasins could be engineered for targeted anti-inflammatory therapy. nature.com/articles/s4146…

Tick evasin proteins block the inflammatory activity of mammalian chemokines. Sstructure-based modification of class A3 evasins alters their chemokine selectivity, suggesting these evasins could be engineered for targeted anti-inflammatory therapy. nature.com/articles/s4146…

Useful chemistry from ticks: Apparently their self-defense chemicals may improve anti-inflammatory drugs. Scientists have discovered a family of tick salivary proteins—A3 evasins—that inhibit inflammation involved w/ atherosclerosis & rheumatoid arthritis phys.org/news/2023-07-n…

1/ Could natural defenses of ticks improve anti-inflammatory drugs? Published in Nature Communications , co-led by BDI’s Prof Stone & Ram Bhusal w/ PhD student Shankar Raj Devkota, researchers have found a new family of tick proteins that fight inflammation. More: bit.ly/3Dkk1dE

"Exciting research published in Nature Communications! 📚🔬 @SankarRajDevk1 et al., have engineered broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins. doi.org/10.1038/s41467…

#OpenAccess #Chemokines #MolecularMedicine Exploring the Unique Chemokine-Binding Properties of Class A3 Evasins from Tick Genus Amblyomma Monash University m.x-mol.net/paper/detail/1…

NEWS: Short peptides derived from anti-inflammatory ‘evasins’ released by ticks could be used to develop new treatments for anti-inflammatory disease. Read more here: nature.com/articles/s4146… Medical Sciences

Proud moment! Our 2 PhD students graduated. They took the project -engineering of tick anti-inflammatory proteins- to the next level. Many congratulations to Pramod Aryal and Shankar Raj Devkota

Extremely excited to be awarded a NHMRC Investigator Grant!

Gelje Sherpa, the man who was guiding a private client up Mt. Everest when he saw someone in distress near the summit. He went up, rolled him up in a sleeping mattress and gave him oxygen. He then strapped the man to his back and trekked 6 hours to safety

Structural Biology Symposium on July 5th! Experts in Cryo-EM, X-ray, protein design, and more. Plenary and invited speakers, oral slots available for MCRs, ECRs, and PhD students, with poster prizes ! Monash Biomedicine Discovery Institute Monash Science Monash Engineering Monash Institute of Pharmaceutical Sciences Hudson Institute

Review article “Cellular Senescence in Lung Cancer” in Ageing Research Review Gabriele De Rubis Shankar Raj Devkota Samir Mehndiratta Gaurav Gupta Sachin Kumar Singh Nisha Panth Kamal Dua Hansbro Research UTS Science UTS Graduate School of Health Centenary Institute IASLC Prevent Cancer Foundation sciencedirect.com/science/articl…

Utilising ticks trick for novel anti-inflammatory drugs!

Check out this review I wrote with Dr. Moumita Dutta in the special issue on "Cryogenic Electron Microscopy of Infectious Diseases" Frontiers in Molecular Biosciences. frontiersin.org/journals/molec… Duke Center for HIV Structural Biology DHVI Structural Biology Duke Human Vaccine Institute Duke University School of Medicine Duke University

That's much deserved.

ARC-funded researchers from COEMinerals: An ARC Centre of Excellence have unveiled a breakthrough: a recyclable peptide that recovers critical metals in one clean step. The achievement was celebrated yesterday at a Parliament House event attended by ARC CEO and staff. Learn more: advanced.onlinelibrary.wiley.com/doi/10.1002/ad…