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Had site initiation out West RadOncResearch for Dr Ryan McMahon's PRIME LUNG pilot Peter Mac Radiation Oncology. 🥳 Interested in #twitterati thoughts re: trial design? hypofrac #radiotherapy or SABR to primary only in 1st line #lungcancer. Baby steps for phase III. Criticism welcome! #radonc

ARREST-2 opened for accrual yesterday! This is a new randomized phase 2/3 trial for patients with >10 mets that hopes to challenge the current radiotherapy paradigm for patients with polymetastatic disease. Thanks to the whole team esp @drdavidpalma and Glenn Bauman, MD London Health Sciences Centre

Great to see the updated BCLC guidelines include RT! RT now incorporated into most major guidelines for HCC (BCLC, AASLD, EASL, NCCN, others) & should be a standard of care option. Full link here: sciencedirect.com/science/articl… OncoAlert

Alison Tree 💙 Nicholas van As Prof Emma Hall Follow us on Bluesky @ICR-CTSU Dr. Andrew Loblaw this is incredible work! perhaps we can collaborate more as our Moffitt Cancer Center group firmly believes the same - namely that improving baseline LUTS prior to RT results in improved urinary function after RT! that’s what #pae is great for! ctro.science/article/S2405-…

This is quite unexpected from a top journal… The Lancet The Lancet Oncology Radiotherapy free is not even the point and main thrust of the paper so why the need to emphasise it as the opener of the title??? Drew Moghanaki Shankar Siva Alex Louie MD, PhD David Palma, MD, PhD

We have become very aggressive in bacterial decolonization to help mitigate oral mucositis in head and neck radiotherapy. It is impossible to say whether both interventions at once are better than either one on their own, but anecdotally I have been pleased. They are essentially

Analysis of MRI use in the diagnostic pathway for #BladderCancer. Nick James also on @Prof-Nick-James.bsky.social The ICR joins Ashish M. Kamat, MD, MBBS MD Anderson Cancer Center to discuss the final #BladderPath trial survival analyses, demonstrating mpMRI introduced upstream of TURBT significantly improves bladder

When I first started in medicine idea of not using arterial line in ICU patient was seen as crazy I remember asking why we couldn't just use cuff for a few hours on particularly busy 30 hour call shift Now we know that cuff BP would've been fine because of an amazing & bold RCT

Elective Pelvic RT for Prostate Ca Alive? Dead? Comatose? Wise or voodoo? East vs West? PSMA vs Not? Answers are here! Biology trumps Bias.

Tony Felefly Jeff Ryckman Mark Storey Colton Ladbury, MD Drew Moghanaki David S Chang Daniel E Spratt Vedang Murthy We are extrapolating everywhere..as Jeff Ryckman told informed patient-guided decision making is the key. And that is why our job might be secured for next 10-15 years probably 😄. Because medicine is still an art at least in prostate cancer.

Radiation dose in SBRT vs. Y90 in HCC. This confused me for the LONGEST time. Both measured in Gy, but clearly not the same – Y90 doses often reach 400Gy+, SBRT doses much lower (<50 Gy), yet both efficacious. Explained below. Bottom line is Y90 Gy ≠ SBRT Gy. OncoAlert

👎 SUPREMO manuscript is out A good example of a trial no longer really relevant to current practice -Routine ALND can be avoided post-AMAROS to save morbidity -Routine chemo not given nowadays (Oncotype etc) ~25% of T2N0 here = dilutes effect nejm.org/doi/full/10.10…

Wow. Huge effect of fish oil on CVD outcomes for patients on hemodialysis! ‼️43% reduction in serious cardiac events ❗Significant reductions in many 2ry end points too 🐟 Standard-ish fish oil (1.6 g EPA/0.8 g DHA) 🌽 Versus corn oil placebo nejm.org/doi/full/10.10…

Radiotherapy plus Long-term Adjuvant Androgen Deprivation with a LHRH Antagonist Versus Agonist in with Very High-risk Localized or Locally Advanced Prostate Cancer: The EORTC GUCG-1414 Phase 3 Randomized Trial sciencedirect.com/science/articl… tombal EORTC

Dear med students & residents: What you're learning matters, but who you’re becoming matters more. The knowledge will come, but now is the time to develop who you want to be as a clinician. Be present with patients. Get to know them. Treat them with kindness. Seek to understand.

A highly original epidemiologic study: in the analysis of never-smoking married couples, lung cancer risk was found to be higher in women. In other words, women may be biologically more susceptible to non-smoking-related lung cancer🤔 lungcancerjournal.info/article/S0169-…

MDT management is the standard of care for early-stage lung cancer and improves survival.

NCCN Breast Cancer Guidelines 2025 (v5) #update focuses on localized therapy: • Less extensive axillary surgery—SLN biopsy may replace ALND in select pts. • Hypofractionated post-mastectomy RT safe with reconstruction. • Partial breast irradiation recommended for low-risk pts

Anthem Blue Cross and Blue Shield ASTRO California Medical Association Physician Association of California Todd Scarbrough Real Doc Speaks Anthony DiGiorgio, DO, MHA Ashley Love Sumrall, MD, FACP, FASCO Bobby Mukkamala, MD ACRO - American College of Radiation Oncology American College of Radiology So this is the response we get from Blue Shield of CA--a nameless, faceless general email address. And no phone number either. No way to ensure continuity or accountability. The tumor is growing. California DMHC

Anthem Blue Cross and Blue Shield ASTRO California Medical Association Physician Association of California Todd Scarbrough Real Doc Speaks Anthony DiGiorgio, DO, MHA Ashley Love Sumrall, MD, FACP, FASCO Bobby Mukkamala, MD ACRO - American College of Radiation Oncology American College of Radiology So Blue Shield of CA granted auth. But I am only allowed to do a 3D plan with one field, or a single arc. how do you do that with the volumes I need to treat? So now I have to do a #P2P to get the codes needed to do it the right way. I would have flunked the boards if I tried to