Paper is published! If you've ever wondered about whether real neurons are anything like the nodes in artificial neural networks... frontiersin.org/articles/10.33…

Excited to share new work from Arthur Sugden and colleagues in Nature Neuroscience using two-photon calcium imaging in visual association cortex to examine offline reactivations of recent sensory experiences during cue-reward learning. ift.tt/3cFX3hz More in THREAD … 1/4.

Replicating experiments in a supercomputer can help us understand the brain 1) We replicated auditory experiments (usually of rat/mice) on a detailed model of the neocortex and discovered novel mechanism for the phenomena observed in the experiments biorxiv.org/content/10.110… THREAD

Beautiful thread by Oren Amsalem from Idan Segev explaining his work! He and his colleagues used a detailed model of the neocortex to obtain cell-type-specific insights on stimulus specific adaptation (SSA) in the auditory cortex. Read it at biorxiv.org/content/10.110…

This new version, allows normalization between samples, reducing experimental variability (assuming assumptions are met!). We used this MATLAB based tool (sorry Fiji users :( ) to correct 2-Photon, Light-Sheet and confocal datasets.

So, I am Happy to share this central effort from my PhD. Pop-Rec is a high throughput method for unbiased, completely automated reconstruction of thousands of neurons from cleared mouse brains. biorxiv.org/content/10.110…

New paper from the lab. The G-clusteron is a model neuron with a single "dendrite" where synapses exhibit distance-dependent multiplicative interactions with each other. It can learn tasks like MNIST via a gradient descent algorithm which makes synapses attract\repel.

In our paper Burst Control, we model the L5PC and analyze the conditions of synaptic activation in the apical and basal dendrites for burst generation. We found a novel burst-class, defined inhibitory control and correlated it with limiting plasticity. biorxiv.org/content/10.110…

My and Menachem Kalmenson's #GradientClusteron paper is out in PLOS CB! Learn how a model #neuron with a single #dendrite can solve #MachineLearning tasks by making synapses attract and repel with a gradient descent rule! With Idan Segev and ELSC Brain. journals.plos.org/ploscompbiol/a…

A new paper by David Beniaguev from my lab. and that of Mickey London using machine learning approach to systematically quantify and compare how "computationally deep" are different neuron types.

New paper from our lab in collaboration with the BBP.

In our paper Burst Control, we explore the synaptic input conditions leading to spike burst firing in layer 5 pyramidal cells doi.org/10.1371/journa… Idan Segev ELSC Brain

I am heading a fascinating endeavor - פרונטירז - מדע לצעירים, a scientific journal for kids, written by prominent scientists and reviewed by kids! This exciting and unique format allows direct interaction between scientists and kids, benefiting both sides. Follow us on twitter!

Join us for an exciting series of talks with Yuval Malchi, in Beit Ariela featuring Amir Amedi, Prof. Sarit Larish, The Bat Lab, Merav Ahissar and myself. Details inside -

My band, Synfire Chain (Band), released our first single! Then we played it to a zebrafish under a microscope with Lilach Avitan ELSC Brain and put the calcium imaging video of its brain as the background to the lyric video. Because #science. youtu.be/vbrnnCXSa_M

Read the paper- Chindemi et al 2022 - A calcium-based plasticity model for predicting long-term potentiation and depression in the neocortex - doi.org/10.1038/s41467… published in Nature Communications Find out more - actu.epfl.ch/news/does-one-… #plasticity #insilico

Human cortical pyramidal neurons are larger, exhibit more complex branching patterns, and feature distinctly nonlinear biophysical properties compared to rat cortical pyramidal neurons. Do these unique characteristics make human neurons more functionally complex? Would that

Will be interesting to hear Christof Koch on "Beyond physicalism - consciousness, quantum mechanics, and mystical experiences."

What makes us human? A new review from my colleagues at the Idan Segev discusses how neuronal modeling can help answer this question. frontiersin.org/journals/neuro…

Our insights from years of modeling human neurons. Come read our new review, now on Frontiers - Neuroscience