We're interested in PAPP-A as an aging target, so we want to understand what it does in different tissues and organs. Unexpectedly, regulating mesenchymal stromal cells is a big part of the answer. Thrilled to see it in print, and congrats to the authors! onlinelibrary.wiley.com/doi/10.1111/ac…

It makes sense: transcription factor binding in vivo is not just specific and non-specific. Supported by new analysis method and comparison of different models.

My first preprint ever is up! 😄 We show that the strength of core promoters, not it's identity (or class, or motifs) determine how it responds to its surrounding genomic environment. biorxiv.org/content/10.110…

All materials from our Machine Learning for Single Cell Analysis workshop (January 2021) are available freely online now, including the lectures. Everything can be found at krishnaswamylab.org/workshop (including a link to the lectures on youtube youtube.com/playlist?list=…) !

Ever feel like UMAP plots are the 2021 version of protein interaction networks? When will we decide that this is just an uninterpretable hairball?

Why are ultraconserved enhancer sequences ultraconserved? Our latest attempt to solve the mystery, led by Valentina Snetkova Here is the TL;DR thread (1/n) nature.com/articles/s4158…

Affordable childcare should be accessible to every parent in our nation. The American Families Plan will make that possible.

We're hiring postdocs. Think deep homology meets proteomics. Discover ancient biochemical systems, invent new tech, or study the structure/function/evolution of proteins in embryonic development. Please RT! Email CV, interests, & references' contact info to [email protected]

more air for MCMC {r-bloggers.com/?p=221825} #rstats #DataScience

Please RT. We are hiring!! computational #postdoc in #singlecell transcriptomics in #Barcelona IDIBELL Programa de Medicina Regenerativa de Catalunya Deadline of applications 13th june. More info 👇idibell.cat/es/ofertes-fei…

I was happy to contribute to the collaborative manuscript Ten Quick Tips for Deep Learning in Biology arxiv.org/abs/2105.14372 1/

Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential biorxiv.org/cgi/content/sh… #bioRxiv

The second edition of ISLR is due out by end of summer! If you are an **instructor** in need of a pre-print to prepare for AY 2021-2022, then send an e-mail to [email protected]

We live in a time where smart people are expected to only say smart things. But to really get the creativity flowing, find a colleague to whom you can say anything, no matter how seemingly naive. Start by asking what is their worst possible idea and see how the thing develops.

"Albert Einstein once said, “You can’t use an old map to explore a new world." "Michael Brent Michael Brent seeks to produce a new map of transcription factor networks in cells" Check out this news story engineering.wustl.edu/news/2021/Draw… via WashU McKelvey Engineering

👏👏👏🤩🤩🤩 Another fantastic paper from the Scaling K2 team!