What if Tregs are not a separate lineage, but part of spontaneously activated T cells? We integrate this idea with our recent findings: Adult T cell leukemia (ATL) is not 'Treg cancer', challenging the current concept of Treg as a distinct entity🧵(1/4) academic.oup.com/discovimmunolo…

After years of research, late nights, and countless experiments, Akhinur Rahman has successfully defended her PhD thesis: “Intragenic viral sequence elements regulating HTLV-1 latency via RUNX complex recruitment.” It was an unforgettable day at Satou Lab - Kumamoto University, @KumamotoUniv_PR.

Out Now! Intragenic viral silencer element regulates HTLV-1 latency via RUNX complex recruitment bit.ly/4mfT8gb #HTLV1 #ViralSilencer #RUNX

Excellent work as usual, Professor Satou and team. Great international collaboration. 👍

We’re now on Instagram, Satou Lab - Kumamoto University @KumamotoUniv_PR! Get a behind-the-scenes look at our research, discoveries, and daily lab life. Follow us: instagram.com/satoulab/ Let’s connect! #Medicine #Biomedicine #Retrovirology #Retrovirus #ResearchLife #SatouLab #KumamotoUniversity

Excellent work from my long-term collaborator of over 17 years, Satou Lab - Kumamoto University 🔬 on Runx/HTLV-1! The start of our collaboration goes back to my own Runx paper in 2007: nature.com/articles/natur… This Runx/HTLV-1 study is the latest milestone 🔬. Honoured to be a co-author 📄✨

Prof. Yorifumi Satou presented a major discovery at #Retroviruses2025 Cold Spring Harbor Laboratory CSHL Meetings – a viral silencer element regulating HTLV-1 latency via RUNX complex. A leap in retrovirology! 🧬🌍 Science knows no borders. #Virology #HTLV #Retrovirus #Japan #CSHL #USA #Retrovirology

We were honored to host Emeritus Prof. Charles Bangham (ScD FMedSci FRS) from Imperial College London at Satou Lab - Kumamoto University 熊本大学 Kumamoto University! He shared insights from his groundbreaking work on HTLV-I, discussed multidisciplinary infection research, and inspired our young scientists. 👏🏼

Join us for an exciting #seminar by our PI, Prof. #YorifumiSatou, a leading #expert in human #retroviruses, as he unveils how intragenic regulation shapes latency in #HTLV-1 and #HIV-1. 🔬 A special thank you to the Kirby Institute, UNSW, UNSW. 🇯🇵🇦🇺 🔗 kirby.unsw.edu.au/events/intrage…

From Ranch to Research Lab! 🐮🔬 Satou Lab - Kumamoto University @KumamotoUniv_PR visited Yatake Ranch (Sugimoto-Honten Group) in Hitoyoshi to meet Dr. Masonori Sugiyama. We’ll collaborate on early detection of BLV, aiming to protect herd health, prevent economic loss, and support the UN SDGs. 🌱🌍

HTLV-1 and HIV-1 share genomic traits but differ in latency. At Kirby Institute, UNSW UNSW, Prof. Satou revealed an intragenic silencer recruiting RUNX1 to suppress HTLV-1 expression. Unveiling HIV-Tocky & HTLV-1 enhancer data, he highlighted distinct integration & latency strategies.

🚀Thrilled to announce our new Tocky-CRISPR-Deep Learning paper! ✅ConvNet + Grad-CAM decodes fluorescent timer (Tocky) data ✅Enables single-cell identification of enhancer-dependent Foxp3 transcription dynamics nature.com/articles/s4146… 🔥A step toward data-driven immunology!

Dr. Masahiro Ono 小野　昌弘 (Imperial College London, UK), together with Dr. Nobuko Irie, Dr. Naoki Takeda, Satou Lab - Kumamoto University, and Prof. Kimi Araki, has unveiled a machine learning-powered method to decode transcriptional dynamics using a Fluorescent Timer system. Nature Communications, doi.org/10.1038/s41467…

Last month, our principal investigator, Professor Yorifumi Satou, was honored to deliver a distinguished international guest lecture at the 19th Biennial Scientific #Conference of the Australian Centre for HIV & Hepatitis #Virology Research (ACH4) in #Sydney, #Australia. 🇯🇵🇦🇺

Big congratulations to Ms. Ishrat Jahan on successfully defending her PhD this afternoon! 🎓👏🔥 Her dissertation has also been published in Microbiology and Immunology (Wiley)! 🧬🐄 📖 doi.org/10.1111/1348-0…

Our lab member, Arif Nur Muhammad Ansori, represented us at the 27th Summer #Retrovirus Conference (#SRC2025) in #Tsukuba, #Japan, where he presented his preliminary work on BLV Cell-Free DNA as a biomarker for EBL, highlighting novel non-invasive approaches in veterinary #virology.

Our research, "Circulating Cell‐Free DNA of Bovine Leukemia Virus: A Promising Biomarker for Enzootic Bovine Leukosis", has been published! Read it here: doi.org/10.1111/1348-0… Don’t forget to follow us! Let’s connect and collaborate! #publishedarticle Wiley in research

Major HTLV-1 findings presented in the UK! 🇬🇧 Prof. Satou revealed viral silencer–RUNX links. Dr. Ishrat Jahan unveiled a new transgenic mouse model. Kudos to our team for leading retroviral innovation! 👏 #Immunology #HTLV1 #JSPS #KumamotoUniversity #Retrovirus #Retrovirology