We reached the mid-way point of the HIP-IMO high school intern program in IMO! Witnessed fantastic mid-term presentations across all 15 interns. Here's the two new students in #EDITLab (Richa & Anish) Read more: labpages.moffitt.org/westj/hip-imo-…

My good friend Sandy Anderson is giving the first KSMB-SMB2024 plenary this morning on the beautiful 건국대학교 campus in Seoul. Great to be here! Indiana University Research #mathonco

Happy Independence day! Enjoy the fireworks and festivities! 🇺🇸

🍫✨ Happy #WorldChocolateDay! Did you know that eating dark chocolate with high cocoa content can deliver fiber, antioxidants and minerals that may lower the risk of certain cancers? Indulge guilt-free! ➡️ Learn about other cancer-fighting foods: bit.ly/4cin6ed

NCI Systems Biology Interested in math models of cancer? 1. Join the #MathOnco newsletter: mathematical-oncology.org/newsletter 2. Read the #MathOnco blog: mathematical-oncology.org/blog/ 3. Download #MathOnco datasets: mathematical-oncology.org/resources/data… 4. Get a #MathOnco job: mathematical-oncology.org/jobs 5. Enjoy #MathOnco art:

NCI Systems Biology that bottom right panel is artwork contributed by Sadegh Marzban. Here's another of my favorite cover art, from him & Gergely Röst:

NCI Systems Biology On new technologies/approaches in #SysBio4CancerResearch: A neat example of how Sadegh Marzban incorporated VALIS into our workflow for Lenia-based spatial models to determine the effect of ECM on immune infiltration (joint work w/ Amelio Lab) Our preprint is here:

I hope I was a good host for you, Hugo. You seemed so thirsty to learn how mathematics contributes to cancer and how MOFFITT is a great place to facilitate collaboration between different scientists.

"Clonal competition in ageing human haematopoiesis and its emerging dynamic fitness landscape" on the Mathoncoblog -- by N. Vincent Mon Père, F. Terenzi, B. Werner - July 30, 2024 mathematical-oncology.org/blog/clonal-co…

This paper has my vote for Most Interesting & Provocative new ideas in "philosophy of modeling" in the last several years: frontiersin.org/journals/immun… My summary: 🧵🧵🧵

A very nice definition of mechanistic math modeling, and why authors use the phrase "knowledge-driven" modeling Provocative: knowledge-driven modeling is a guess at the input-output relationship

Knowledge-driven models can & should be combined w/ machine/deep learning Four broad/abstract classes: sequential, parallel, extrinsic, intrinsic

All these approaches are under the umbrella of Mechanstic Learning combining the advantages of knowledge (mechanistic models) and data (machine/deep learning models)

Just on time for labor day weekend (for those of you State-side) Jeffrey West writes about mechanistic learning, the best of two worlds based on a paper by John Metzcar Paul Macklin Alvaro Köhn-Luque Catherine Jutzeler-Walter and Sara Bruningk: mathematical-oncology.org/blog/mechanist… #MachineLearning #MathOnco

Such an amazing day with Jeffrey West and Ari Barnett at Moffitt Cancer Center for Mascots at Moffitt/#MilesForMoffitt Spirit Day! 🎉🏃‍♂️ #FightCancer #AmazingResearchGroup

Tracing the history of Mechanistic Learning & why I like the approach… On the Mathoncoblog mathematical-oncology.org/blog/mechanist…

Excited to use Morpheus software developed by @BroadInstitute in our latest study! We applied a Mechanistic Learning approach to highlight the critical role of cell state transitions between stem-like CD34+/CD38- and leukemia states. Stay tuned! 🧬 Check out here if you want to

My group is interested in the Mech-Learn approach to identify patient-specific parameters that are most predictive of clinical outcomes. We’ve found Morpheus to be a useful first step into Mechanistic Learning:

Excited to announce that registration for the 12th IMO workshop on Treatment Toxicity is now open. Held onsite Moffitt Cancer Center Nov 3-Nov 8 #MoffittIMO more details: imo12.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 09/30!

A new Moffitt study offers a new perspective on antifragility, proposing a unified framework for understanding the property across different complex systems. See how this study, led by Jeffrey West, PhD (Jeffrey West) and in collaboration with investigators from the international