Sarah Pendlebury (@st_pendlebury) 's Twitter Profile
Sarah Pendlebury

@st_pendlebury

Consultant Physician and Professor of Medicine and Old Age Neuroscience. Oboist and publicity officer for the Radcliffe orchestra

ID: 1339330222387294208

calendar_today16-12-2020 22:03:15

29 Tweet

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Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

This is the real challenge: real world implementation of optimal delirium care at scale. It’s taken >10 years to get screening embedded across our acute trust. It may take 10 more years to develop systems to ensure positive screens are reliably actioned. Digital health may help?

Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

Yes, a great overview of existing protocols. Agree that next step is to determine the impact on actual rates of assessment. Then whether the assessments result in actions...

Masud Husain (@masudhusain) 's Twitter Profile Photo

OK, so we Brain definitely thought we need to celebrate this: 50 years since the advent of CT with the first brain scan performed at Atkinson Morley Hospital, Wimbledon. Find out more bit.ly/2Ty3a3k

Martin Vernon (@runnermandoc) 's Twitter Profile Photo

Older people living with frailty or who lack a caregiver to attend assessments with them may not have equitable access to videoconference-based virtual care It’s not all rosy in the blooming new digital garden.. 👇

Alasdair MacLullich (@a_maclullich) 's Twitter Profile Photo

❓ When should patients with #delirium be followed-up? 🟡 Concerns about underlying dementia 🟡 Persisting symptoms on discharge 🟡 Risk of post-traumatic stress symptoms ℹ️ More info: the4at.com/deliriumguide

❓  When should patients with #delirium be followed-up?

  🟡 Concerns about underlying dementia

  🟡 Persisting symptoms on discharge

  🟡 Risk of post-traumatic stress symptoms

ℹ️  More info: the4at.com/deliriumguide
Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

Agreed. This is an important consideration in using the CFS in the acute context. We’ve recently introduced routine CFS in acute medicine but some clinicians are clearly guestimating whether patient can do the shopping from an acute hospital bed...

Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

We are building ours into the electronic patient record. The risk level (high vs not) will then be displayed in real time. The idea is that the patient can be managed according to the risk (of both unrecognised prevalent delirium and risk of incident delirium).

Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

Useful review showing that frailty interventions in hospital are likely effective. More trials are needed but the big challenge is how to identify frailty in real time at scale and to implement interventions across the acute hospital, not just in “specialist” areas.

Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

Chairing at WSC with Eric E Smith on World Stroke Day: Great state-of-the-art talks on screening for VCI, predicting dementia after stroke, bio markers and mixed dementia from Natalia Rost @nsanar, Geert Jan Biessels, Suda Seshadri&Chris Chen. On demand at worldstrokecongress.org

Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

Agreed- very informative contribution to an understudied and yet prevalent issue in #dementia. Again, acute pressures and competing demands were cited as a factor impacting staff responses as seen elsewhere in #dementia and #delirium.

Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

Pleased to share our recent OXVASC paper showing how routinely acquired brain imaging informs delirium risk (and possibly mechanisms) Utility of white matter disease and atrophy on routinely acquired brain imaging for prediction of long-term deliriu… pubmed.ncbi.nlm.nih.gov/34793588/

Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

We are currently recruiting to a large multidisciplinary team working on an exciting and innovative 5-year NIHR funded dementia research programme: jobs.ac.uk/job/CYZ339/res… jobs.ac.uk/job/CYZ347/res… jobs.ac.uk/job/CZA545/pos… jobs.ac.uk/job/CYX183/dat…

Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

With thanks to Emily Boucher, Rhodes Scholar for her great work on our study on the prevalence and prognostic value of frailty in the acute setting. The Clinical Frailty Scale performed at least as well as more complex measures supporting current guidance Kenneth Rockwood Ragnhild Munthe-Kaas

Stroke AHA/ASA (@strokeaha_asa) 's Twitter Profile Photo

Cognitive Impairment After Ischemic and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association/American Stroke Association ahajournals.org/doi/abs/10.116… @nsanar Sarah Pendlebury Hugo J. Aparicio, MD, MPH, FAHA @gottesman_lab Eric_Smith_VCI AHA Science

Cognitive Impairment After Ischemic and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association/American Stroke Association ahajournals.org/doi/abs/10.116…

@nsanar <a href="/ST_Pendlebury/">Sarah Pendlebury</a> <a href="/hugoapariciomd/">Hugo J. Aparicio, MD, MPH, FAHA</a> @gottesman_lab <a href="/VCI_EricSmith/">Eric_Smith_VCI</a> <a href="/AHAScience/">AHA Science</a>
Colm Cunningham (@cunningham_colm) 's Twitter Profile Photo

Fantastic to see this important study out now in BRAIN. Leiv Otto Watne's Delirium research group in Oslo: Impaired glucose utilization in the brain of patients with delirium following hip fracture academic.oup.com/brain/article/…

JAHA (@jaha_aha) 's Twitter Profile Photo

Infection, but not acute inflammatory biomarkers, is linked to post-stroke cognitive impairment. Infection may be a potential therapeutic target. #AHAJournals Elise Milosevich @NeleDemeyere Sarah Pendlebury ahajrnls.org/4903qK2

Infection, but not acute inflammatory biomarkers, is linked to post-stroke cognitive impairment. Infection may be a potential therapeutic target. #AHAJournals <a href="/EliseMilosevich/">Elise Milosevich</a> @NeleDemeyere <a href="/ST_Pendlebury/">Sarah Pendlebury</a> ahajrnls.org/4903qK2
Sarah Pendlebury (@st_pendlebury) 's Twitter Profile Photo

Infection, delirium, and risk of dementia in patients with and without white matter disease on previous brain imagi… pubmed.ncbi.nlm.nih.gov/38310893/ WMD impacts the infection-dementia association but not the delirium-dementia association: implications for mechanisms and VaD prevention