Professor Jian Lu's lab's research in eLife reveals: Upstream open reading frames buffer translational variability during Drosophila evolution & development. #PKUResearch doi.org/10.7554/eLife.…

Zengyi Chang laboratory reveals that an intrinsic (cis) disassembly element in FtsZ protein regulates the dynamic formation of the bacterial cell division ring (Z-ring). #PKUResearch rdcu.be/epsC6

Junyu Xiao's lab reveals how BTN3A1, BTN3A2, and BTN2A1 work together to activate Vγ9Vδ2 T cells for novel γδ T cell therapies! #PKUResearch doi.org/10.1016/j.immu…

Prof. Wensheng Wei's lab employed high-throughput screening based on prime editor at both population and single-cell levels to identify and characterize functional synonymous mutations in human cells. #PKUResearch nature.com/articles/s4158…

Peking University scientists decode RNA's "dark matter" to expand the genetic code, precisely programming protein function for next-gen therapeutics. #PKUResearch doi.org/10.1038/s41586…

How are cilia built? Using cryo-ET, Qiang Guo and team captured basal body biogenesis & axoneme assembly in mouse ependymal cells at sub-nanometer resolution. #cryoET #TEAMTOMO #PKUResearch nature.com/articles/s4146…

A novel receptor for AAV (AAVR2, carboxypeptidase D), which is distinct from the multi-serotype AAV receptor (AAVR) has been discovered and characterized. #PKUResearch cell.com/cell/fulltext/…

Structural study reveals how CD163 forms calcium-dependent oligomers to bind Hb–Hp complex, facilitating ligand uptake via endocytosis. #PKUResearch nature.com/articles/s4146…

Deng and colleagues pioneered a robust chemical reprogramming method to directly convert human blood cells into pluripotent stem cells.#PKUResearch doi.org/10.1016/j.stem…

Symposium on RNA: Mechanisms and Therapeutics Focus on recent advancements in RNA mechanisms and therapeutics. Ready to join us? #PKU #PKUResearch 🗓️September 25-27, 2025 📍JW Marriott, 83 Jian Guo Road, Chao yang District, Beijing Register Now: meeting.csbmb.org.cn/PKU_RNA_FORUM.…

RNA circularization is key for circRNA therapeutics. Wensheng Wei' s lab unveils PIET & CIRC. Using intact self-splicing introns, CIRC generates circRNAs efficiently — even large RNAs encoding full-length dystrophin. #PKUResearch nature.com/articles/s4146…

Hsiang-Ying Sherry Lee’s group and collaborators uncover how composite transposons (SVAs) with dual histone marks act as RNA-dependent regulators to drive erythropoiesis, steer blood lineage commitment, and shape hematopoietic aging. #PKUResearch cell.com/cell/fulltext/…

Xiong Ji's group reveals that INO80/SWR remodelers regulate gene expression by reshaping chromatin landscapes and modulating BRD2 binding, rather than through H2A.Z dynamics. #PKUResearch academic.oup.com/nar/article/53…

He Yu's group and their collaborators revealed the geographic and temporal origins and subsequent dispersal and admixture of pigs in East Asia, mirroring human migration and agricultural development history. @PKUResearch doi.org/10.1093/molbev…

Ph.D. Programs at Peking University School of Life Sciences Admissions for 2026 Are Now OPEN💗 Welcome to the School of Life Sciences at Peking University. Let’s embark on a journey together to unravel the mysteries of life! Peking University bio.pku.edu.cn/en/index/index…

Peking University Life Sciences -- A Century in the Vanguard. Welcome to watch the documentary of Peking University Life Sciences.📺 Peking University School of Life Sciences, Peking University

Breakthrough in biologics engineering! Research from Junyu Xiao's lab decoded the hexameric structure of frog IgX via cryo-EM & hacked human IgM/IgG to form super-efficient hexamers. #PKUResearch doi.org/10.1126/sciadv…

Zhe Zhang’s group presents cryo-EM structures of the glucose-6-phosphate transporter SLC37A4—whose defect causes glycogen storage disease type Ib—in multiple functional states, revealing its mechanisms of substrate transport, inhibition, and pathology. doi.org/10.1038/s41594…

Congratulations to Prof. Deng Hongkui and Prof. Qu Lijia from the School of Life Sciences at Peking University on their election as academicians of the Chinese Academy of Sciences (CAS)!

Xiong Ji's group revealed that FeaSion decodes the regulatory landscape and functional diversity of RNA polymerase II CTD phosphorylation. #PKUResearch science.org/doi/full/10.11…