If you feel bad about a rejected grant 🧻, just remember: Arthur Riggs & Keiichi Itakura asked the NIH for ~$300k to clone the human somatostatin gene into E. coli (a guinea pig project before moving to insulin.) It was rejected. The NIH called it "an intellectual exercise."

If it looks like a duck, swims like a duck, and quacks like a duck, then it depends on the context.

Made it 😫

I am pleased to share our latest work on the role of NRF2 in beta cell expansion during neonatal ages in Diabetologia. Thank you Mindich CHDI for providing the trainee pilot award that assisted me in developing this project and to all collaborators. link.springer.com/article/10.100…

Based on 149 case scenarios from clinical providers in Canada, the UK, and India, AI outperformed primary care physicians in patient diagnostics. The future is here...😮 arxiv.org/abs/2401.05654

I am thrilled to announce that our article titled 'NRF2 is required for neonatal mouse beta cell growth by maintaining redox balance and promoting mitochondrial biogenesis and function' has been featured on the cover of Diabetologia this month.

Our March cover shows a pancreatic islet labelled for insulin (green) and #NRF2 (red). In this issue, Baumel-Alterzon et al report that NRF2 plays a significant role in the neonatal burst of #betacell proliferation and survival Sharon Baumel-Alterzon link.springer.com/article/10.100…

My laboratory is currently seeking a PhD student with a background in molecular biology to conduct research on the interaction between Entamoeba histolytica and the microbiome. The position will commence in August-September 2024 or later.

All the influencers are losing it over the new report that intermittent fasting is associated with a 91% increase in heart disease death. Obviously many caveats, and not published yet so don't know what other flaws exist, but this seems like a pretty big effect and probably worth

Congrats Anoop! Nice work.

Boston-Ithaca Islet Club 2024

Boston-Ithaca Islet Club 2024

Single cell regulatory architecture of human pancreatic islets suggests biological sex differences in β cell function and the pathogenesis of type 2 #diabetes #insulin biorxiv.org/content/10.110… DREAM_Theme

Excited to share our publication in Science Translational Medicine. Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system. science.org/doi/10.1126/sc…

Mentors are worth their weight in gold. Find mentors who believe in you and are willing to bring up your name and put you forward for opportunities - even when you’re not in the room.

Excited to present my research the(sugar)science "Ask the Expert" on July 25th. I am anticipating a thoughtful exchange of ideas. Thanks Sharon Baumel-Alterzon U-M Medical School Research Zoom link: us02web.zoom.us/meeting/regist… #proinsulin #proteinfolding #betacells #insulin #diabetes

I am thrilled to announce that I will be opening my own lab in Oct 2024 at City of Hope. The Baumel-Alterzon lab will explore the importance of redox regulation in beta-cell life. We're looking to recruit passionate scientists at all levels—stay tuned for more info.

www2.breakthrought1d.org/site/TR?fr_id=…

Don't miss the last talk of the year! Yuval Dor on RNA editing

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has