My preprint on continuous optimization of structure using observational and interventional data is out! This is work with Jingyou Rao Sriram Sankararaman Harold Pimentel . arxiv.org/abs/2305.19215 (1/n)

Excited to share my new preprint that I’ve been working on in Xiao lab! Grace Xiao We present editing agnostic tool to identify dsRNAs from long-read sequencing!! biorxiv.org/content/10.110…

Excited to share our latest work Genome Biology . Great collaboration w/ Ali Mortazavi lab. L-GIREMI as a tool for direct identification of RNA editing sites in long-read RNA-seq, PacBio genomebiology.biomedcentral.com/articles/10.11…

Really proud of Ryo! Great work that started from a rotation project! Students out there: rotations do turn into publications sometimes, enjoy the journey!

Our paper looking at cell-free DNA epigenetic features in ALS is now out in MedRxiv! I am extraordinarily grateful for the ALS patients who participated in the study. This research would not be possible without them medrxiv.org/content/10.110…

New review from the lab, led by the talented Elaine Huang, where she beautifully delineated the contributions of epitranscriptomes to host immunity. Thanks to Clara Frydman for assisting. tinyurl.com/22a9tede

RNA modifications play key roles in host immunity (some of which can be leveraged in cool ways for things like the design of cancer therapeutics) ... you can learn more about computational methods to study these events in my review paper, now out in Genome Research 🧬

Attending #eshg2024 in Berlin!! Excited to see lots of European science here I am presenting poster on the 3rd at P16.055.C about cell type specific transcript atlas. Come check it out!!

had the pleasure of presenting my work yesterday at #eshg2024 in Berlin! looking forward to learning a lot the rest of this week

Had a great time at #eshg2024!! Thank you for organizers for making great science gathering happen! pc Lena Krockenberger

1/ Hi all, I am really excited to share our new computational method: IsoLASER! Key findings are highlighted below in this thread. Special thanks to the co-authors Dr. Kofi Amoah Kofi Amoah and Dr. Grace Xiao Grace Xiao who made this work possible.

Our work on studying genetic architecture of expression, splicing and RNA editing in Schizophrenia is now out in HMG! Check it out academic.oup.com/hmg/advance-ar…

Our work on genetic variants that affect RNA stability is out in Nature Genetics! We present the RNAtracker computational pipeline, which can distinguish between transcriptionally- vs. stability-mediated regulation of gene abundance. bit.ly/42aihk2 (1/n)

Excited to announce our paper in Nature Communications! 🚀 rdcu.be/eNw6b We present IsoLASER, a stand-alone method leveraging long-read RNA-seq to separate genetic and trans-acting influences on splicing. Grateful to co-author Kofi Amoah and my advisor Grace Xiao #RNA