The odds of thrombosis or bleeding did not differ between patients who received AT repletion or prophylactic anticoagulation. ow.ly/8Mxk50WVhQU

أحدث التقنيات في تشخيص وعلاج الأمراض النادرة في مستشفى الملك فيصل التخصصي وبإشراف نخبة من الخبراء المتخصصين في مختلف المجالات

BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

The immune system is powerful. Sometimes, too powerful. If it goes unchecked, it can turn on us - attacking our own organs, tissues, even our blood. That’s why the 2025 Nobel Prize in Medicine matters so much. It honors three scientists who figured out how the body stops

Taking you on a tour through a full house bone marrow for JAK-2 positive MPN! 🏠🔬 Panmyelosis everywhere — and look at those megakaryocytes taking over! 🤯🩸

The first principle is that you must not fool yourself and you are the easiest person to fool.

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2025 #NobelPrize in Chemistry to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal–organic frameworks.”

“My parents could barely read or write. It’s been quite a journey, science allows you to do it.” New laureate Omar Yaghi was in the middle of changing flights when we reached him, just after he heard that he had been awarded the 2025 #NobelPrize in Chemistry. In this interview

Patients with sickle cell disease often wait hours for pain relief in the ER when triage doesn’t follow guidelines. Proper Emergency Severity Index (ESI) scoring can dramatically improve access to medication. ow.ly/ZsRE50X8C8F #ConquerSCD #SickleCell

Beyond Platelet Counts - Assessing Safety of Post-Splenectomy TPO-RA Use in ITP | VuMedi vumedi.com/video/recent-p… via @vumedi

A simple oral drug that ⤴️ HbF and still remains one of the most impactful therapies in sickle cell care 💪🏽 The humble hydroxyurea 🙌🏽 ⤴️HbF = ⤵️HbS Hydroxyurea = ⤴️NO = ⤵️vascular injury nejm.org/doi/full/10.10…

In 1992 Peter Ratcliffe received this rejection letter from Nature. His findings were not "a sufficient advance in our understanding". 27 years later he won the Nobel Prize for the same discovery. Don't lose faith in the things you believe in.

New study uncovers how sickle cells expose a lipid signal that fuel anemia, clots & pain crises. Deoxygenation triggers PIEZO1→Ca²⁺→TMEM16F→PS exposure. Blocking PIEZO1 (w/ anti-gout drug!) breaks this harmful chain. doi.org/10.1002/ajh.70…

{الَّذِينَ آمَنُوا وَتَطْمَئِنُّ قُلُوبُهُم بِذِكْرِ اللَّهِ ۗ أَلَا بِذِكْرِ اللَّهِ تَطْمَئِنُّ الْقُلُوبُ}

#Halloween2025 Really scary.

One recommendation I make over and over is to use a prophylactic DOAC instead of aspirin in newly diagnosed myeloma. Just choose a DOAC [they are getting much more affordable!]! *⃣Risk scores lack validation for choosing VTE ppx. 😀The BENEFIT trial shows 6-month incidence of

Low-VAF JAK2 V617F signals: early disease? benign clone? something in-between? Check out our latest study, we explores the clinical correlates and clonal behavior of these subtle findings Naseema Gangat Ahmed AlNughmush Mohammad M. Alhousani, MD AmericanJournalofHematology #MedTwitter onlinelibrary.wiley.com/doi/10.1002/aj…

Paroxysmal Nocturnal Hemoglobinuria (PNH) Mayo Clinic Proceedings Mayo Clinic Hematology-Oncology Fellowship AA&MDSIF mayoclinicproceedings.org/article/S0025-…

Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3 | New England Journal of Medicine nejm.org/doi/full/10.10…

IACH News of the Week • November 11, 2025🗞️ Mohamad Mohty IACH Topics: - ROPEG in ET (SURPASS ET trial) - JAK2mut VAF low and very low - DEC-C in TP53 MDS - MAGIC-ONC: IV catheters guide iach.org/news-of-the-we…