Timely reminder...

While I’m a big fan of new technologies that help us study human biology…there’s still no replacement for animal research! I wrote an article outlining this in Genetic Engineering & Biotechnology News genengnews.com/topics/transla…

Jason Shepherd Genetic Engineering & Biotechnology News Submit concerns by 5pm ET 7/14 go.pardot.com/e/858023/ducin…

You're not depressed, you just need a quest.

Grant terminations have grabbed the headlines and have seen legal action, but even more damaging to the US research enterprise has been the massive decrease in research grants issued by federal agencies NIH: -57% in the number of awards and -63% in value compared to FY24

Woha Kaun Hai Tera..Musafir (Guide 1966) #melodica #melodicacover #roli ... youtu.be/mbnk-U9V6Nc?si… via YouTube

If you're tired of AI and stuff...we published CRISPR-based protocols that you can actually use to delete alpha-synuclein (~100% efficiency) or knock it into endogenous locus (~53% eff) in cultured neurons: star-protocols.cell.com/protocols/4339

So much of American #science has been lost already...more in store.

America must remain a global leader in science. That’s why I joined my Senate GOP colleagues in urging OMB to release NIH funds Congress has already appropriated for critical research in cancer, heart disease, and rare disorders.

Grateful to Meg Tirrell and CNN for covering this story. My NIH grant to study hearing loss was abruptly canceled, then restored by a court, but NIH hopes to terminate the grant AGAIN(statnews.com/2025/07/06/hhs…), creating massive uncertainty for my trainees. We're in a golden age

This is insane.  If this holds and 50% of all grants are suddenly required to be funded for full five years instead of one year (and it sounds like this policy will pass, given the quote from Battacharya?), that means even without any ostensible budget cut, NIH funding next year

Vought has ordered a halt on all extramural NIH funding for the rest of the FY. No words. You cannot let this stand Senate Democrats Senate Republicans Jay Bhattacharya, MD, PhD Andrew D. Huberman, Ph.D. wsj.com/politics/polic… Trump Administration Puts New Chokehold on Billions in Health-Research

Amidst this chaos, current paylines have been revised due to "multi year funding" and many grants that were administratively pending (means funding being prepared") have been deemed unfundable. These were the best ideas extensively vetted by reviewers and council.

capito.senate.gov/contact/contac… collins.senate.gov/contact/email-… britt.senate.gov/contact/share-… cassidy.senate.gov/contact/get-in… mccormick.senate.gov/share-your-opi…

"The multi-year funding scheme only makes sense if the goal is to threaten the American research enterprise" scienceandfreedomalliance.substack.com/p/a-quiet-poli…

"..only in the absence of habitual comforts, without ways we cushion against hard facts of our own nature and mortality, do we befriend ourselves and discover what is most alive in us. The contrast, painful at first, becomes a clarifying force.." themarginalian.org/2020/04/13/her…

Signs of new life amidst carnage. Postdoc Leo Leonardo Parra-Rivas (left, Brent on right) is heading East to U Maryland University of Maryland School of Medicine as an Asst Professor with the Institute for Neuroscience Discovery (medschool.umaryland.edu/um-mind/)

Silence of the Labs washingtonpost.com/business/2025/…