First approval for a #CRISPR therapy in the world. UK MHRA has authorized Exagamglogene autotemcel (Casgevy) this morning. What a historic and uplifting day for patients and for the gene & cell therapy field. gov.uk/government/new…

Happy Holidays from the Wilson Lab ❤️❄️ I wonder what Santa will be DELIVERing for us 🎅🏾🎄

Excited to share a milestone in our forward genetics developments! Today in nature we report massive mutagenesis screening in T cells with base editors, increasing resolution from genes to nucleotides nature.com/articles/s4158… A @MarsonLab story with my dear friend Carl Ward 1/10

Here in this winter wonderland at Banff 🇨🇦 for the Keystone conference on Precision Genome Engineering #KSGenomeEng24 #KSNADelivery24 I’ll be presenting a poster on peptide mediated delivery of CRISPR RNPs in T cells tomorrow, stop by if around (poster 2526)! Ross Wilson

The Wilson lab has two new PhD candidates: 🍾 Congrats 🍾 to Brigette Manohar and Christy George on passing their UC Berkeley MCB qualifying exams! They're both working to improve CRISPR delivery, potentially enabling new therapies for the central nervous system.

CRISPR has the potential to cure many genetic diseases, but it’s notoriously hard to use in neurons. In this work we tackled 2 of the main hurdles: Cas9 delivery and DNA repair. And we discovered… The rules of genome editing are different in neurons👇🏾 biorxiv.org/content/10.110…

New Strategy Enhances CRISPR Editing Efficiency for Therapeutic Use In a new April 2025 The CRISPR Journal published study, IGI UC Berkeley researchers leverage new constructs for NLS sequences to improve editing efficiency in human immune cells #crispr hubs.li/Q03hZVqv0