🔥Telegram İfşa

🚀 New cryoEM breakthrough! Affinity-grid method with streptavidin on a lipid monolayer enhances particle absorption and reduces air-water interface exposure. Resolved unique left-handed open spiral structures of MCM3 and MCM3-ATP-dsDNA complexes. nature.com/articles/s4146…

Thrilled to share that our Zorya paper is now published online in Nature! It was an incredible team effort Philipp Popp Marc Erhardt SimonJackson —thank you to everyone who contributed to this work.Inga Songailiene Victor Klein-Sousa Aritz Roa Freddie Martin Yong Wang Alexander Harms ₳źiż

Congratulations haidai HU and the rest of the team!!! 🎉🎉🎉🎉

Our work describing the structure and mechanism of the Zorya anti-phage defense system is finally out nature! Led by haidai HU and Philipp Popp in a wonderful collaboration with Nicholas M. I. Taylor Lab, SimonJackson, Alexander Harms et al.! nature.com/articles/s4158…

More ribosome structures solved by RAPPL (collaboration with slavica pavlovic djuranovic and Yaser Hashem Labs). This one is novel bacterial ribosome structure from 2ml culture and using method described in our preprint. biorxiv.org/content/10.110…

Best read of the day - innovative design, and great science to generate large virus-like protein cages by breaking symmetry 🎉 nature.com/articles/s4158… nature.com/articles/s4158… nature.com/articles/s4146… Quinton Dowling, Sangmin Lee Ryan Kibler King Lab Institute for Protein Design

Gisele Pelicot will forever be the face of dignity and resilience. Her bravery is truly remarkable — and she has empowered millions of women around the world. Today, we stand with all survivors of sexual violence and against the systems that intimidate them into silence.

This photo made my day. Solidarity with #GiselePelicot and all survivors.

Protein purification with light via a genetically encoded azobenzene side chain "the UV light-switchable cis/trans-isomerization of the ncAA Pap enables one-step protein purification" nature.com/articles/s4146…

Feeling festive? The Smart Biology team reveals our most viewed animations of 2024. Press like if our top 10 picks make your holiday brighter! To start it off at #10, the dinosaur hiding in the rough endoplasmic reticulum. #Biology #3D #Education #Animation🎄🎬

Our #Top10 Countdown rolls on with 2024s most viewed Smart Biology animations! Landing at #2 is our animation of mRNA export. Stay tuned for #1 tomorrow and keep learning! ow.ly/ywT350QlksK #biology #3D #animation #education #EdTech

I've done something stupid. Something I advise others not to do. I've read the comments underneath a climate-related post on X. So now I'm going to address some of these comments in a thread (because no-one should amplify this stuff by replying to it). 🧵

Det er for groft! Lars Løkke Rasmussen misbruger nu Danmarks alvorlige sikkerhedssituation til at lancere nye planer om at sønderskære velfærden og sende hårdtarbejdende danskere senere på pension, mens han samtidig vil bruge milliarder på at forgylde sine venner i

New pre-print - 🥳🥳🥳 biorxiv.org/content/10.110…

Contractile injection systems are used by bacteria as tools to survive, compete and interact with their environment, check out our pre-print detailing one discovered in Salmonella. Nicholas M. I. Taylor Lab cryoEM Papers CPRatUCPH Claudia Kielkopf Freddie Martin Marta Siborova Eva Maria Steiner-Rebrova 🇺🇦🇦🇹🇸🇪

Excited to see our work published in Science Advances! We present RBPseg, a method for structural prediction of #phage receptor-binding proteins. We applied it to diverse tail fibers and validated the predicted structures using #cryoEM. Read here: science.org/doi/10.1126/sc…

"The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation" Now published Nature Microbiology 🥳! rdcu.be/eugWM

New study shows how bacteria evolved powered-up propellers imperial.ac.uk/news/265473/ne… ... nature.com/articles/s4156…

Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out NatureStructMolBiol🥳rdcu.be/eBbrH Massive team effort led by Leonie Anton Meseret Haile Wenjing Cheng in collaboration with Jerzy Dziekan alan cowman #teamtomo

Next up Fundamental research in phage biology with Dr. Nicolas Taylor. Very cool work on Zorya anti-phage defense.