1/ Did you know the genome might have hidden protein-coding genes? In the 25 years since the Human Genome Project, research has been tied to a consensus set of 20,000 protein-coding genes. But the ‘dark genome’ has ‘dark proteins’ lurking in plain sight. biorxiv.org/content/10.110…

The entire city of Wrightwood, California, is under an evacuation order as webcam footage from Mountain High Ski Resort shows the #BridgeFire burning through the resort. Multiple fast-moving wildfires are beginning to impact communities across Southern California.

POV: It maybe seem sunny in Los Angeles at the moment, but most of Orange, San Bernardino, and Riverside Counties feel utterly apocalyptic right now, smothered by smoke from THREE major wildfires currently burning out of control, threatening lives and property.

Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles coated with the fusogenic FAST protein: Cell cell.com/cell/fulltext/…

Biologists would love to be able to read out the amino-acid sequence of any protein molecule as they would the letters of a sentence. A system in which a biological motor pulls proteins through a pore brings the dream closer to reality go.nature.com/3MHf43i

A single genomic change may have given modern humans an advantage over more ancient contemporaries like Neanderthals by enabling increased neocortical neurogenesis, a 2022 Science study found. Learn more in this #SciencePerspective: scim.ag/8jv #ScienceMagArchives

#bridgefire #wrightwood this was interesting last night

At meeting this week, NIAID News's Jeanne Marrazzo said of recent bird flu case in Missouri: - "quite nervous" about case - "predisposition to pulmonary infection" - no contact to anything "remotely" tied to H5N1 - CDC can't sequence much because high CT tinalexander.github.io/notes/2024/09#…

Incredible photo of the #BridgeFire in the mountains behind downtown Los Angeles.

That dog looks like a cat

Heroic Rescue Caught on Camera ❤️🚒 Watch as one of our brave Battalion Chiefs risks it all to save a woman walking through the flames of the #AirportFire. This incredible rescue shows the dedication and courage of our firefighters, who are working tirelessly to keep our

Novavax Availability Update 📢 Here's the inside scoop on what's happening with Costco's distribution of Novavax JN.1 this season. As of September 10, the first batch of doses arrived at the national distribution center of their wholesaler. In the next few days, the doses

We've been sequencing wastewater for 2.5 years. In 2024, H5N1 started showing up. Our findings are published in the New England Journal of Medicine. Sequencing-Based Detection of Avian Influenza A(H5N1) Virus in Wastewater in Ten Cities w/ Texas Epidemic Public Health Institute (TEPHI) nejm.org/doi/full/10.10…

A seed excavated from a cave in the Judean desert was germinated. It grew into a tree from the Commiphora family, used to make frankincense and myrrh. This paper says it may be a "lost" source of Judean Balsam that is mentioned often in the Bible but disappeared ~800s AD.

First look at the genome sequence of Greenland shark to find possible clues that could explain their mind-boggling extreme lifespan of up to 400 years. - 70% of the genome is repetitive elements - many uniquely duplicated genes, many related to DNA repair pathway - p53 is not

Breakthrough work Mike Tisza & colleagues sequencing wastewater to surveil for epidemic-risk pathogens like #H5N1 This should be scaled nationwide now to monitor H5N1's spread & potential evolution for human transmission & become a staple of surveillance for epidemic threats

I have a YouTube playlist for molecular biology for my undergrad interns in the lab. I might as well share it here. youtube.com/playlist?list=…

23andMe is considering takeover proposals! I wonder who is going to grab it. It's a great resource that will become valuable in the long term. seekingalpha.com/news/4148832-2…

Our app CellWalk is featured on the iOS App Store!! Ahhh, so exciting! #education #science #biology #iosdev

Cataloging "naturally variable exons" in GTEx "Using GTEx tissue transcriptomes from 838 individuals, we identified 56,415 exons which are included in mRNAs in some individuals but entirely excluded from others, which we term 'naturally variable exons' (NVEs)." Fascinating!