Roger Greenberg
@rogerrogergr
The Greenberg lab investigates processes that affect genome integrity and how they influence human biology
ID: 917456591716339752
http://www.med.upenn.edu/apps/faculty/index.php/p8145566 09-10-2017 18:27:51
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“Overcoming Immune Heterogeneity in Ovarian Cancer” by Dmitriy Zamarin, MD, PhD, Associate Professor, Section Head of Gynecologic Medical Oncology, and Precision Immunology Institute of Icahn School of Medicine at Mount Sinai #ScientificSymposium24
Excited to share our latest finding: TCAF1, an ion channel regulator, has a novel role in fork protection during replication stress! Huge congrats to Lingzhen, Chen and Shan and all co-authors! Big thanks to David Piston ⚡ Ben Major Nima Mosammaparast for their incredible support!
We enjoyed a great lineup of talks yesterday for our PCGI Annual Scientific Retreat at the Penn Museum Penn Museum. Huge thanks to our speakers, especially keynote speaker Don Cleveland (UCSD), and faculty keynote speaker Xue Sherry Gao Xue Sherry Gao!
Here is our recent work now published in Nature Communications showing how replication stress and inflammation coordinate with each other during the onset of senescence. Thanks to my mentor Philippe Pasero and current and past members of PaseroLab ! www-nature-com.insb.bib.cnrs.fr/articles/s4146…
Excited to share that our paper on transcription repression after DNA double-strand break is online. Great collaboration with Taekjip Ha and Yang Liu, spearheaded by Shuaixin He Biophysics Dept@Johns Hopkins Med BCMB Graduate Program at JHMI cell.com/cell-reports/f…
embopress.org/doi/full/10.10… Excited to share our latest publication in EMBO Journal on TDP1 phosphorylation at S61 in mitosis and genome instability and Cancer. Congratulations Srijita!! for her incredible PhD work. DSTIndia SERB Department of Biotechnology ICMR Indian Association for the Cultivation of Science
I am seeking an enthusiastic postdoc to join my lab in Sydney to work on Nuclear Dynamics, DNA repair and genome stability. We offer innovative science, a competitive salary, and a supportive team. If you are interested, please get in touch with me: [email protected]
The Basser Global Prize honors a visionary scientist who has conceptually advanced BRCA1/2-related research that has led to improvements in clinical care. Nominations will be accepted by 8/16/24! Find nomination package details and more here: spr.ly/6013cxErx Penn Medicine - Abramson Cancer Center
Interested in base damage repair or homologous-recombination or perhaps both? Check out our review where we discuss communication between the two pathways and its implication in therapy response! sciencedirect.com/science/articl… Fantastic job by graduate student Lindsey Aubuchon Washington U. DBBS
Super nice and comprehensive perspective in Science Magazine written by CarmineSettembre@lab summarising the papers from my lab and Samuel Bakhoum Melody Di Bona.
Delighted to share our latest preprint where we describe first-in-class DUB #MolecularGlues by Francesca Chandler et al. Another amazing collaboration with Roger Greenberg Professor Francesco Del Galdo and Jo Salvino labs. biorxiv.org/content/10.110…
Amazing efforts from the first author Francesca Chandler showed the mode of action by #cryoEM where 2 small molecules glue a 16-subunit protein complex. Animation credit Jeroen Claus Phospho
Francesca Chandler Jeroen Claus Phospho In collaboration with Roger Greenberg and Professor Francesco Del Galdo teams we showed molecular glues inhibit interferon signalling in cells. A tour de force effort funded by Wellcome and others, and enabled by our amazing research facilities. The Astbury Centre The Wistar Institute Penn Medicine