Mayo Clinic’s fully automated AI-enabled pathology slide digitization operation, the largest in the world, is reinventing the practice of pathology by scanning 36,000 slides a day and converting these assets to a multimodal platform of data: mayocl.in/4dzL2KT

AI can be used to make convincing looking fake data. There is no way we can distinguish real from fake anymore. It is safe to assume that genAI has already resulted in many fake papers. Scientific publishing is not prepared for this.

Pomona College is hiring a tenure track assistant professor in computational neuroscience! cc Neuromatch academicjobsonline.org/ajo/jobs/27999

1/n 🚨 🧬Our paper on the role of #mitochondria and free radicals in promoting the collapse of #Cancer #micronuclei is out in Science Magazine today. A story led by the brilliant Melody Di Bona it started with a simple question: why do micronuclei rupture? science.org/doi/10.1126/sc…

In vivo CAR T-cell generation in nonhuman primates using lentiviral vectors displaying a multidomain fusion ligand Blood Journal Umoja Biopharma doi.org/10.1182/blood.… doi.org/10.1182/blood.…

New research from katherlab on #computational #pathology: We benchmark pathology foundation models 👇 Several of these are publicly available under permissive licenses. arxiv.org/abs/2408.15823 Some takeaways: 1. The vision-language model CONCH (Faisal Mahmood) outperforms

Register! Broad Institute Machine Learning for Drug Discovery broad.io/mldd Oct 31/Nov 1 In-person, or free virtual attendance! Speakers: Jennifer Listgarten James Collins Jakob Uszkoreit Jian Tang Mila Antonia Mey Jakub Tomczak Henry van den Bedem Nicolas Stransky

#pathology #AI twitter - is there a mature pathology AI with similar #functionality as #ChatGPT or #Gemini but custom trained? Available via website, open to general public, easy access 😍

#singlecell experts - what is your experience in #singlenuc vs #singlecell sequencing, from #human tumor samples? We have cryopreserved cells (from the tissue), and also snap frozen tissues, so we have option to do either, but I have been debating on which one to pursue. We

Interested in estrogen/anti-estrogen regulated gene expression, and anti-estrogen resistance in #breastcancer? Check out EstroGene2.0 estrogeneii.web.app a free user-friendly website hosting publicly available data in a simple search format. 🧵biorxiv biorxiv.org/cgi/content/sh…

The advancement of #ChatGPT in the past 12 months has been phenomenal. Last year, I tested it with simple bugs introduced in my code and it could not figure it out. Today, it resolved a complex bug in my code, and produced the correct results. They never got it at first round,

Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation dlvr.it/TDL5VW

Happy #MidAutumnFestival2024 !! 祝大家中秋节快乐 团团圆圆 万事如意🥰

With PBMCs we know that single nuclei doesn’t capture all of the states we see in single cell (e.g. it’s much easier to identify CD4 T cells in single cell). Do we know how true this is in other tissues? I’d love to see papers on sc vs sn cell states in non-immune celltypes :)

In 2014 I joined the fledgling Tumor Microenvironment Center UPMC Hillman Cancer Center w Robert Ferris, MD, PhD and @VignaliLab, taking a holistic view of cancer by unifying faculty interested in a ‘piece’ of its environment (now 7 investigators!). Today, I announce that we are GROWING! 1/

DNA copy number variation is strongly buffered at the protein level. The buffering is much stronger than at the RNA level.