While Raynaud's phenomenon severity is worst at very cold temperatures, it may also worsen during very warm temperatures, presumably due to air conditioning. Based on q3mos assessments of 2243 RP pts (88% female, 82% White, mean 55 yrs buff.ly/3Xd01n3

"Vanishing Fingers" Acro-osteolysis in a patient with Scleroderma and renal failure and bilateral hand pain. Causes of AO include Scleroderma, PsA, hypertrophic osteoarthropathy, skeletal dysplasias, frostbite, Hyperparathyroidism, genetic disorders buff.ly/3MuuzLV

Running with Data (8.30.2024) Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com - including tips on steroids, MAS, and myositis testing. buff.ly/3XdUJaV

Register for the Advances in Rheumatology and Technology Symposium, taking place THIS WEEK!! 9/6 to 9/8 in Chicago! Conference Chairs Drs. Orrin Troum and Alvin Wells Dr. Alvin Wells bring together a dynamic mix of rheum topics. buff.ly/4e7Py2T

Dactylitis is seen in 50% of PsA patients. Dactylitis is frequently associated with more severe PsA phenotype, often representing the initial feature of the disease. Many agents are effective but no b/tsDMARD is distinguished as being superior in dactylitis.

RA Experts (Drs. Wells, Troum, Wright, Broadwell) discuss dose response differences in treating RA. Watch this video sponsored by Genentech! buff.ly/3yUqAoV

Points to Consider when Managing Inflammatory Arthritis with Cancer buff.ly/4e9J1F6

Learn more about the 2023 EULAR recommendations and what these may mean for your patients with #Lupus. Listen to this podcast presented by Dr. Narender Annapureddy #SponsoredbyGSKUSMA buff.ly/3AJbfbk

Sustained Hydroxychloroquine and Cardiovascular Outcomes A national cohort study shows that continuous use of hydroxychloroquine (HCQ) protects against cardiovascular (CV) events in patients with systemic lupus erythematosus (SLE). buff.ly/4dPwtD1

Good Clinical Practice Recommendations on Glucocorticoid Withdrawal and Adrenal Insufficiency The European Society of Endocrinology and Endocrine Society have jointly published a clinical guideline on the diagnosis and treatment of glucocorticoid-induced adrenal insufficiency,

Metanalysis of Social determinants of health and lupus nephritis (31 studies) showed poor LN outcomes were 1.47-fold higher w/ any adverse SDoH. Also multiplicative impact of having two or more adverse SDoH on LN outcomes. buff.ly/4gfNGqD

Prospective Nurses' Health Study (n 204,175) included 212 w/ incident SLE; ultraprocessed food intake was assoc w/ >50% increased SLE risk & doubled risk for anti-dsDNA Abs. Sugar-/artificially sweetened drinks assoc w/ lupus risk (HR 1.45) buff.ly/3X7EGLA

Claims analysis, shows <0.5% of IBD or RA pts developed an invasive fungal infx within 1 year of TNF therapy initiation (. Histoplasmosis was the most common IBD = 3.3 IFI/100PY RA = 2.8 IFF/100PY buff.ly/3XdUYCP

Study of 4370 RA pts (26534 PYs) saw 362 MACE (CV) events. RA activity & inflammatory markers assoc w/ MACE risk in bDMARD non-users (not those on bDMARDs). 515 bDMARD vs 3855 non-users (n=3855). Each DAS28-CRP unit incr MACE risk (HR 1.21)buff.ly/47dn1Xq

EMA Updated overview of leflunomide (Arava) buff.ly/3z7f0qq

Immunomodulatory Prevention of Uveitis Relapse in Behçet's The results of a randomised, open-label, head-to-head trial shows that adalimumab was superior to ciclosporin in preventing uveitis relapses in patients with severe Behçet's disease. buff.ly/3APiUVr

Hear experts’ roundtable discussion with Dr. Alvin Wells, Dr. Orrin Troum, Dr. Grace Wright, and Dr. Aaron Broadwell in this podcast sponsored by Genentech. buff.ly/4easock

Scleroderma Raynaud's May Worsen in Summer Episodes of Raynaud's phenomenon, a common feature of systemic sclerosis (SSc, also known as scleroderma), were more severe not only at low temperatures, as one would expect, but also during summertime heat, a multinational study

Singapore study of Autoimmune (AIRD) risk w/ COVID infx compared 104 179 DELTA + pts vs 666 575 PCR neg controls (~80+% Vax) & 375 903 Omicron+ vs 619 379 controls (~75% boosted). Found no signif incr risk of AIRD w/ COVID infx. buff.ly/47d73wD

Is it possible that Helicobacter pylori (Gm neg) can exacerbate or cause RA? Infx of gastric epithelial cell line w/ H. pylori upregulated the expression of PAD4 and increased PAD4 activity, leading to Helicobacter pylori-induced citrullination? buff.ly/3Xv9w29