On #LiverDay , we're exploring the ties between liver's health and Telomere Biology Disorders (TBD) 🧬. Did you know shorter telomeres might indicate a higher risk for conditions like cirrhosis?🔍Learn more about!
bit.ly/3O1nC3u
bit.ly/3oD0ZIf (chapter 18-19)

Happy #DoctorsDay2024 to all the incredible physicians who dedicate their lives to healing and hope! 🩺💙 At Repeat Dx, we also proudly support #NationalDonateLifeMonth this April. It is a month to remember, celebrate, and encourage organ donation. #DonateLife #ThankADoctor 🌷💚

Excellent talk by Kristen Schratz (Johns Hopkins) at the 9th international BMFS symposium AA&MDSIF !Not all that glitters is gold‼️Be careful when evaluating short telomeres.Telomere length should always be interpreted in the context of the entire clinical picture 🔝🔝🔝

AA&MDSIF
1/3Wonderful opening session on Genetics & Genomics of #BMF
Closing comment from real world perspective. If insurance does NOT cover WGS or #telomere length testing what path can a clinician take?

The length of one small structure in our lymphocytes could be a huge factor in fighting aplastic anemia. It's exciting to see how telomeres may guide physicians toward more effective treatments! 👀 #AplasticAnemia #Telomeres #MDS
bit.ly/3SEmc2G

@Repeatdx supports #RareDiseaseDay . 'Exploring the Power of Rare!' a fitting title for a blog that aims to raise awareness and understanding of rare diseases. Check it out and gain insight into the world of rare diseases. 🦓
bit.ly/3kqx7R3

What do you wish people understood about your Super Rare condition? 'I'm still me.' - Paula, living with Dyskeratosis Congenita, a rare genetic disorder
#RareDiseaseDay #RareDiseaseDay 2024

People with either very short or very long telomeres are at increased risk of developing cancer – this is called the Telomere Length Paradox. #Telomeres
#WorldCancerDay

bit.ly/3XZthwc

@Repeatdx supports #RareDiseaseDay . 'Exploring the Power of Rare!' a fitting title for a blog that aims to raise awareness and understanding of rare diseases. Check it out and gain insight into the world of rare diseases. 🦓
bit.ly/3kqx7R3

Genomic instability, shortened telomeres, and the impact of cancer therapies on both cancerous and healthy cells - all factors to consider when selecting the best treatment for those with telomere biology disorders. #telomeres

bit.ly/3tVlzKh

Early diagnosis of TBDs can make a huge difference in treatment outcomes. Flow FISH analysis is highly sensitive and specific for TBDs. Therefore, PGPs can make strides in diagnosis and treatment.
#telomere
#ILD
bit.ly/3OacQdQ

Who needs a cape when you have a cheer bow? Becca's journey as a cheerleader took a detour when diagnosed for aplastic anemia, later, a telomere test led to Dyskeratosis Congenita. Props to Suneet Agarwal Lab for dedication to telomere diseases. #Telomere
on.bchil.org/3O7cyVj

What is the future of telomere length testing in telomere biology disorders?
excellent article by Drs. Sonia Bhala & Sharon A. Savage, M.D. bit.ly/474ZDda
Telomere length testing and germline genetic testing are both essential pieces of the TBD diagnostic puzzle.
#Telomeres

But be careful: the classical DKC trias is rarely seen in adult #TBDs … at the same time, #TBDs are still severely underdiagnosed in adults. Therefore, don’t forget to screen newly Dx BMFS for #telomere length ! Team Telomere Uniklinik RWTH AC lichterzellen

Simona Colla from MD Anderson Cancer Center presenting our NIH NHLBI National Cancer Institute USP Universidade de São Paulo collaboration on U2AF1 as a driver of malignant transformation in #telomere biology disorders at the germline predisposition workshop! #ASH23 ASH Fernanda Gutierrez-Rodrigues Neal S Young M.D. Sharon A. Savage, M.D.

Clinical manifestations of telomere biology disorders in adults ashpublications.org/hematology/art…

From the brainchild of Chad Newton and with Deji Adegunsoye, MD, PhD, out in ERS publications:

Telomere length <10th percentile predicts increased mortality in fibrotic HP and unclassifiable ILD pts exposed to immunosuppression - just like in IPF.

erj.ersjournals.com/content/62/5/2…

When to suspect adult #telomere biology disorder #TBD #ASH23