Improving frozen section evaluation of procurement donor #kidneybiopsies and reducing the discard rate: a promising role for artificial intelligence doi.org/10.1016/j.kint… Original article: doi.org/10.1016/j.kint… Cedars-Sinai Academic Medicine #KICommentary #renalpath #transplantation

Uric acid crystals/microtophi: - associated with gout - occur in deep medulla - collecting ducts - can migrate from tubular lumens to interstitium - can have a granulomatous reaction - basophilic and polarizing when examining frozen sections From Dr. Biederman @renalpathsoc

Nice example of striped fibrosis which is often attributed to chronic CNI toxicity in kidney transplant biopsies. #renalpath #pathtwitter

🌡️ As climate change accelerates, extreme heat is no longer a seasonal nuisance; it’s a silent health crisis. One of its most devastating and overlooked consequences? Chronic Kidney Disease of unknown etiology (CKDu). A new study from Odisha, India, published in KIReports,

Proud to see latest work on ANCA-associated vasculitis led by Professor David Jayne (#CITIID & Cambridge University Hospitals NHS) published in KIReports. Read more⏬

Our review “The Role of Complement in Normal Pregnancy and Preeclampsia” is out! We dive into pathophysiology (in mice & humans), touching on genetics, diagnosis, mgmt, key controversies, & unmet needs. A joy to work with Richard Burwick, MD, MPH & #JeanRegal frontiersin.org/journals/immun…

Anti-CD38 Daratumumab Treatment of Chronic Active Antibody-mediated Kidney Allograft Rejection KIReports #openaccess buff.ly/57VFpIm

Prospective Pilot Study of Plasma Cell–Targeted Therapy With #Bortezomib in Refractory IgA Nephropathy #IgAN #VisualAbstract by Krishna Penmatsa kireports.org/article/S2468-…

The arsenal just keeps looking to expand for IgA Nephropathy!

Do non HLA antibodies matter in #transplant?

🧬 New publication! "Utility of Genetic Information for Management in Kidney Transplantation and Living Donation" We discuss how genetic testing informs kidney transplantation, precision care and donor selection. 📄 Read here: authors.elsevier.com/a/1lRzTzcYo6Ci8 #Genetics #KidneyTransplant

Patient with multiorgan failure. Diagnosis & treatment?🦉

Exome sequencing in Saudi Arabian pediatric kidney disease single-center cohort KIReports #openaccess buff.ly/dx2RSDm

Fibrosis in IgG4-related disease due to the overexpression of early growth response-1 (EGR-1) by Epithelial cells that facilitates tissue fibrosis buff.ly/fnQ14E7 buff.ly/94QmII9

NEW on the #AJKDBlog: Timothy Yau interviews Roger Rodby and Bill Whittier about a recent AJKD Review focusing on measurements of proteinuria. bit.ly/4oax9Zh (FREE)

🔬📷 Uromodulin Cast ~ Pale and irregularly shaped cast material with "frothy" appearance, and surrounded by inflammation (due to extravasation) ~ #RenalPath #Pathology #Kidney

📢 Our new paper is out in Autoimmunity Reviews! We review how social determinants of health #SDH shape outcomes in #lupus — across the full patient journey — and explore solutions. Huge thank you to Zoe & Lena from Lupus Europe and Laurent ARNAUD ! 🔗 doi.org/10.1016/j.autr…

#RenalPath: The collapsing pattern in collapsing glomerulopathy is evident here, with accentuation of each lobule due to the collapse of the tuft. There is also overlying glomerular visceral epithelial cell hyperplasia with protein droplets. bit.ly/2LapiYx (Free)

A Clinico-Pathologic Approach to Glomerular Diseases: schematic by Laura Mariani American Society of Nephrology GlomCon #BRCU2025 nephsim.com/image-gallery/… #Nephrology #FOAMed

Kidney Cysts in Autosomal Dominant Polycystic Kidney Disease and Alport Syndrome: Two Familial Cases Illustrating Diagnostic Challenges bit.ly/Bais25CR Ron Gansevoort #ADPKD