Self-therapeutic gold nanopaticles for psoriasis treatment🌿🌿

Offaly good – A pig kidney has been successfully transplanted into a human for the first time #NBTintheNews via The Economist economist.com/science-and-te…

New paper! Cells secrete #extracellularvesicles to communicate and we make #nanomedicines with EVs. Congrats postdoc Hanzhuang for reporting in Nano Letters a molecular probe for imaging EV secretion live in medium! No EV isolation or transfection needed! pubs.acs.org/doi/abs/10.102…

Biomarkers found in blood and urine can potentially provide more information, more easily and frequently, than a tissue biopsy. #Adfeature with Illumina

The key question for developers of SCD therapies is whether +ve effects on acute symptoms will translate into meaningful durable protection against organ damage - it will take time for a clear picture to emerge But some v. good work now underway in what was once a neglected area

CUHK researchers from CUHK Engineering and CUHK Medicine develop a new #goldnanoparticle, which can downregulate the genes that are linked to epidermis hyperproliferation and inflammation, as a self-therapeutic treatment for #psoriasis. Nano Letters bit.ly/3GpOjLL

Check our new piece of review on drug-free/self-therapeutic metal-based nanoparticles for managing inflammatory diseases😀😀

Inflamed heart tissue after myocardial infarction can be repaired via an intravascularly infusible degradable matrix that binds to leaky vasculature. rdcu.be/c3g8Z [N&V] rdcu.be/c3g9f [Paper]

🔥 New paper alert!🔥 Our work on folic acid-conjugated gold nanoparticles for treating renal fibrosis is online PNASNews. I am indebted to Cecilia Chan for her resilience and collaborators Prof. James Lau, CC Szeto, and my team for support since 2016. pnas.org/doi/10.1073/pn…

Drug and Delivery are ‘what’ and ‘how’ of therapeutic products. Without knowing ‘what’, ‘how’ is irrelevant. And without answering ‘how’, ‘what’ is not possible. Check out an overview of the evolution of drug delivery technologies over the years nature.com/articles/s4155…

Drug delivery systems can be designed to improve cell therapies! In their new Review, Samir Mitragotri et al discuss the engineering of drug delivery systems at various scales to improve the efficacy of therapeutic cells Samir Mitragotri Harvard SEAS Wyss Institute go.nature.com/4f7J1qr

New content online: Synthetic polypeptides inhibit nucleic acid-induced inflammation in autoimmune diseases by disrupting multivalent TLR9 binding to LL37-DNA bundles dlvr.it/TC5jw2

New content online: Acid-degradable lipid nanoparticles enhance the delivery of mRNA dlvr.it/TCH2NP

Official Kavli Prize 2024 Photo with King Harald V of Norway

New paper alert🔥! DNA/RNA nanostructures are exciting drug carriers. Reese and Zhihui reviewed how they interact with cells in vivo! Thanks Chuanbin Mao_phage_group for editing this special issue for the 60th birthday of The Chinese University of Hong Kong - CUHK in Advanced Materials. onlinelibrary.wiley.com/doi/abs/10.100…

A circular RNA aptamer shows therapeutic efficacy in vivo in a psoriasis model go.nature.com/3UeBGf2 rdcu.be/ebBhp

Causes of hypertension

Spotlight on cancer immunotherapies go.nature.com/3XUTPkM

Polyethylene glycol immunogenicity in nanomedicine bit.ly/4mYcPcL