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If you are interested in the highly dynamic quaternary structure of peroxiredoxins, take a look at our new paper... pnas.org/content/early/…

Thank you, Ari, Bruno and Madia Universidad de la República for writing an insightful commentary on our recent peroxiredoxin paper. pnas.org/content/early/…

Specific redox signaling needs a scaffold. Check out our new paper on the Prx2-STAT3 redox relay... Nature Communications nature.com/articles/s4146…

N-acetylcysteine (NAC) is widely used as an "antioxidant". But do we understand what it is doing inside cells and organisms? Check out our review, by Brandán Pedre, @Vladi76320028 and Daria, now at Messens Lab: sciencedirect.com/science/articl…

If you want to detect protein persulfides you need to trap them first… here we share a story that started with puzzling observations and led to new insights into the behavior of alkylating agents. Thanks to Aubry K. Miller for the nice collaboration. onlinelibrary.wiley.com/doi/10.1002/an…

All across biology, cells produce hydropersulfides (RSSH). But why? We found them to scavenge free radicals and protect biomembranes Nature Chemical Biology. Many thanks to our collaborators José Pedro Friedmann Angeli Ferroptosis (SPP 2306) Almut Schulze 🧬🔬 Aubry K. Miller Frauke Graeter go.nature.com/3DpjDvO

Great to see mutually confirming and complementary research on hydropersulfides as outstanding radical scavengers from The Pratt Group J. Am. Chem. Soc. along with our's Tobias Dick Nature Chemical Biology. pubs.acs.org/doi/10.1021/ja…

How stressed tumor cells escape cell death: Scientists at the German Cancer Research Center have now discovered a new mechanism by which normal as well as #cancer cells protect themselves against ferroptosis. Tobias Dick ➡️bit.ly/3RSTGsQ

News and Views Nature Chemical Biology: Jon M. Fukuto discussing new insights into the cytoprotective roles of hydropersulfides: "A radical way to avoid cell death" nature.com/articles/s4158…

Happy to write this CellChemicalBiology Spotlight with MikeLange highlighting recent exciting work from Tobias Dick, The Pratt Group, and colleagues. Their findings reveal a role for hydropersulfides as endogenous antioxidants that inhibit ferroptosis! 👏🎉🤩 cell.com/cell-chemical-…

Congrats to The Pratt Group Tobias Dick Almut Schulze 🧬🔬 José Pedro Friedmann Angeli for discovering the role of hydropersulfides and other sulfane sulfur compounds in #ferroptosis -- My thoughts about sulfur and the brain are here: brentstockwell.medium.com/can-sulfur-sav…

We are looking for a new #PhD student to work on #persulfides and their role in #ferroptosis, as part of Ferroptosis (SPP 2306). #PhDposition #RedoxBiology #ChemicalBiology #DKFZ #UniHeidelberg dkfz.de/en/redoxregula…

"In the Pipeline" Science Magazine: Derek Lowe reflects on “Weird Little Sulfur Groups”, inspired by our new paper on protein persulfidation Nature Chemical Biology nature.com/articles/s4158… science.org/content/blog-p…

Oxidative inactivation of GAPDH is a booster for reductive power. Tumor cells employ this mechanism to survive in the host and to resist therapy. Many thanks to our long-term collaborators Ralser Lab, Mick Milsom & Pavlo Lutsik nature.com/articles/s4225…