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Some good news U of T Mississauga going into the long weekend: Read about some of the wonderful work by #UTM grad students & postdocs, the recent prize winners recognized for research & leadership, and all of the festivities at the 2022 Graduate Research Colloquium. uoft.me/7Zb

The Centre for Medicinal Chemistry U of T Mississauga is growing into an international research hub for #drugdiscovery in #Ontario! Read more in the Perspective #Mississauga special feature inside the The Globe and Mail! ➡️ perspective.ca/u-of-t-mississ… #business #innovation #entrepreneurship

Congrats Rebecca Allan, PhD on being named a 2022 PRiME - Precision Medicine Initiative at UofT Fellow for her project on allosteric first-in-class DNAJ-PRKACA inhibitors for the treatment of fibrolamellar hepatocellular carcinoma!! So well-deserved to be counted among these stellar scientists! prime.utoronto.ca/news/2022-prim…

Interested in doing small molecule #drugdiscovery in Ontario? The Gunning Group is looking for a postdoctoral researcher in #medicinalchemistry University of Toronto to design, synthesize, and evaluate small molecules as targeted therapeutics. Please RT! #chempostdoc #postdocjobs Chemjobber

U of T Mississauga's magazine The Medium published a wonderful feature on our amazing postdoc @anna_thechemist! Anna is a dedicated scientist and an inspiring advocate for Black Women in STEM, founding the non-profit Empowering Female Minds in STEM. Read her story here! themedium.ca/dr-anna-ampaw-…

Check out this feature on Max's Big Ride in The Medium! We're so grateful to have grad students like Rebecca Allan, PhD and recent grad Yasir S. Raouf who are committed to developing histone deacetylase (#HDAC) inhibitors for Duchenne muscular dystrophy (#DMD). #DefeatDuchenne

The next PRiME 2022 Fellow Spotlight is Rebecca Allan, PhD, a PhD Candidate in the @Gunninglabuoft and co-supervised by @Lsalmena. She is working on identifying novel ligands for fusion proteins implicated in rare diseases!

Reliving elementary school field trips at #InnovatorsBall Ontario Science Centre with the Amplitude team (incl PRiME - Precision Medicine Initiative at UofT fellow Rebecca Allan, PhD!) ⚛️🧬🦇🔬

Amazing to see PRiME Fellow Rebecca Allan, PhD & PRiME Associate Lamisa Ataei attending RBC Innovator Ball! Way to go #besttrainees! 💃🏻💃🏼#womenintech #WomenInScience #Thanksgiving #inspiration

This UTEST startup is tackling one of the biggest problems faced by #AIresearch - the alignment problem. SilicoLabs - Capture Behaviour are making waves in the U of T Arts & Science community & beyond with their no-code research software. U of T Research University of Toronto Entrepreneurship Creative Destruction Lab (CDL) artsci.utoronto.ca/news/psycholog…

PRiME - Precision Medicine Initiative at UofT Fellows Lightening Talks at #PRiMESymposium2022. 3 min talks - challenge successfully accomplished! 👏👏👏#newprojects #newideas #innovation #BestFellows

Congrats to all PRiME Fellows for nailing their Lightning talks at the PRiME - Precision Medicine Initiative at UofT Symposium today! Our PhD student Rebecca Allan, PhD shared exciting progress in the development of first-in-class inhibitors for the fusion kinase DNAJ-PRKACA in fibrolamellar hepatocellular carcinoma!

The Gunning Group is hiring a postdoctoral researcher in synthetic #medicinalchemistry University of Toronto to design, synthesize, and evaluate small molecules as cancer therapeutics in the Centre for Medicinal Chemistry. Please RT! #chempostdoc #postdocjobs utm.utoronto.ca/cmc/

Calling #chemtwitter and #medtwitter: TODAY is the last day to vote on our ERANET video and we are 70 LIKES AWAY FROM FIRST PLACE!! Please like and share the video so we can share our latest JAKSTAT-Target research at the 2023 ERANET symposium in Romania! youtu.be/DIDkmqQg-Do

Thanks Rebecca Allan, PhD for showing our support of Max's Big Ride to raise awareness and funding for #Duchenne muscular dystrophy! Last week saw the first approval of a gene therapy for #DMD, and we're excited to share a small molecule #HDAC inhibition strategy in the coming months!

This is just one of the labs at U of T Mississauga and University of Toronto where your donations go! Very exciting to hear about the progress they are making. #research #duchenne #dmd #musculardystrophy

We are so proud of Rebecca Allan, PhD for defending her thesis on the discovery of ligands for rare diseases like fibrolamellar hepatocellular carcinoma & Duchenne muscular dystrophy! Becca is a meticulous & driven scientist with a passion for research translation & entrepreneurship.

Thrilled to share our story on the first rationally designed #covalent #HDAC inhibitor! YSR734 uses an SNAr-reactive electrophile to engage a noncatalytic nitrosylation site cysteine in #HDAC2, showing in vitro activity in AML & #DuchenneMuscularDystrophy! pubs.acs.org/doi/10.1021/ac…

This is amazing! Huge congrats to everyone involved and thank you for all your hard work!!

Check out our preprint on an #AI-powered #ligandability prediction platform for bottom-up analysis of #chemoproteomic data to identify #covalent binding sites, including cryptic sites, for the discovery of novel drug targets. #proteomics #MachineLearning chemrxiv.org/engage/chemrxi…