Rapé Lab
@rapelab
molecular mechanisms of cell fate specification in development and disease; molecular glues and induced protein degradation as new therapeutic options
ID: 3002756670
http://mcb.berkeley.edu/labs/rape/ 30-01-2015 04:04:28
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Waving goodbye to Diane Haakonsen, who will start her own lab University of Toronto soon! Thank you for your amazing discoveries (stress response silencing!), your mentorship, and your all-around-great team play!
To my knowledge, that's the first RING-E3 ligase inhibitor that targets the catalytic domain. Through an awesome intramolecular glue. The idea of targeting RING-E3s with molecular glues goes back to a white paper that TCG bet on almost 15 years ago, resulting in Nurix Therapeutics. 🙏💪
New preprint from Christina Woo's lab Harvard Chemistry, underscoring that CRBN is a quality control E3 ligase that recognizes proteins cleaved through Asn/Gln cyclization. biorxiv.org/content/10.110…
My university won 23 medals at the olympics. Congratulations to all our outstanding student-athletes at UC Berkeley !!!
Earlier this month, the Doudna Lab held its 30th (!) reunion, hosting alums for two days of science, fun, and reminiscing! It's been a RNAissance indeed.
We are hiring! An exciting opportunity for a Research Officer (Cell Biologist) to join our team at ACTT in Bundoora (Melbourne) is now available! ACTT's mission is to develop novel targeted protein degrader drugs to transform the lives of cancer patients: wehi.wd3.myworkdayjobs.com/WEHI/job/Bundo…
Thank you so much, Alessio, Yogesh Kulathu, and the students at MRC PPU and Centre for Targeted Protein Degradation. What a wonderful visit, filled with so much exciting science!!
Wonderful story by Cherry Yen of 中央研究院 Academia Sinica in Nature Communications, describing an elegant method based on protein stability to follow formation of large complexes in cells! Congratulations!!! nature.com/articles/s4146…
Welcome UC Berkeley MCB #MolecularTherapeutics students to a new semester!!! Excited that our MTx major undergrad class describing the life of a drug from discovery to approval is starting today! Taught by the amazing Dan Nomura Roberto Zoncu Fyodor Urnov. Enjoy the ride!
Packed house for the first day of class, UC Berkeley MCB "Therapeutic Discovery and Development" (MCB120)!!! Taught by an absolutely all-star team: Dan Nomura, Roberto Zoncu, Fyodor Urnov. It's going to be an awesome semester! 🤩🔥
Excited to teach this innovative class with Dan Nomura and Fyodor Urnov . Enrollment 50% up from last year’s first edition. Passion for drug discovery runs deep UC Berkeley!
UC Berkeley produces more funded new businesses than any other university. Go Bears. pitchbook.com/news/articles/… UC Berkeley UC Berkeley SCET BHEP Berkeley SkyDeck Bakar BioEnginuity Hub Bakar Fellows
Thank you so much, Michael Fischbach Michael Fischbach Stanford University, for giving an inspiring first MTx seminar of the 24/25 season! And thank you to all in MTx UC Berkeley MCB UC Berkeley for showing your love of translational biology in a standing room only talk with 20 minutes of questions! 👏
Michael looks very, very skeptical as I am introducing him, but he recovered an gave a spectacular I-want-to-run-to-the-bench-to-do-science talk after that! Thank you Michael Fischbach