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new paper by Kevin Boehm (precision medicine AOC student) assembled huge dataset of MHC-1 binding peptides (1M+), built predictive model (ForestMHC), tested accuracy using new mass spec data bmcbioinformatics.biomedcentral.com/articles/10.11… code here github.com/kmboehm/Forest…

Exciting new work from @Hepworth_Lab. Congrats!

**IMMEDIATE OPENING** Advanced #IBD #Fellowship opportunity at Weill Cornell for July 2019. Also interviewing for 2020. Seeking a graduating fellow/recent grad seeking a world class opportunity at the Jill Roberts Center for IBD @WCMC_IBD email [email protected] to apply

Randy Longman Anand Kumar, MD Robbyn Sockolow MD Weill Cornell Medicine GI & Hepatology

Very proud of our @WCMC_IBD and Weill Cornell Medicine GI & Hepatology team for this Gastroenterology publication on #COVID19 in #IBD patients. ⬆️GI sx, steroids + active disease are risk factors. Prevalence ~24% in NYC cohort. Anand Kumar, MD Randy Longman Reem Sharaiha, MD MS gastrojournal.org/article/S0016-…

Baseline Disease Activity and Steroid Therapy Stratify Risk of COVID-19 in Patients with Inflammatory Bowel Disease gastrojournal.org/article/S0016-… Dana Lukin MD, PhD this study and the VA study I just tweeted are very reassuring

Potential role for diet and the microbiome in lupus Hospital for Special Surgery (HSS) Medha Barbhaiya

Happy Friday! Here is today's algorithm for this week's #MondayNightIBD discussion on Infliximab Loss-of Response in UC by Adam C. Ehrlich, MD, MPH, FACG. My take home point: We need more comparator RCTs! Aline Charabaty, MD, FACG, AGAF #IBDAlgorithm.

Thanks to the Starr Cancer Consortium for funding our research on composite mutations in bladder cancer patients. Proud of Weisi Liu Kyrillus Shohdy, MD who initiated this work in my lab. Excited to collaborate w Gopa Iyer David B. Solit, MD @sloan_kettering #ctDNA #base_editing #teamscience

FT. @MasonMount_10's goal wins it for the Blues! 👌 #FULCHE

AIEC #metabolism drives inflammation: Propanediol metabolism by #Crohns disease adherent-invasive #Ecoli promotes intestinal #Tcell inflammation. CX3CR1 mononuclear phagocytes sense propionate to trigger IL-1β leading to tissue #inflammation Randy Longman cell.com/cell-host-micr…

Congrats team! #WCMC_IBD cell.com/cell-host-micr…

Additional evidence that how the mucosal immune response deals with adherent bacteria is central to microbiome tolerance vs. inflammatory immunity. AIEC adaptation to mucus is key. Longman Lab Weill Cornell Medicine Cell Host & Microbe cell.com/cell-host-micr…

New study identifies an “Achilles heel” of bacteria linked to Crohn’s disease that may lead to more targeted therapies, according to a team of researchers from @WCMC_IBD, Cornell University, Weill Cornell GSMS, NewYork-Presbyterian, @sloan_kettering, led by Dr. Randy Longman. bit.ly/3oNI5vR

Weill Cornell Medicine @WCMC_IBD Cornell University Weill Cornell GSMS NewYork-Presbyterian @sloan_kettering Randy Longman Great work @WCMC_IBD Randy Longman and team!

Transferable iga-coated odoribacter splanchnicus in responders to fecal microbiota transplantation for ulcerative colitis l... - Lima S et al. - dx.doi.org/10.1053/j.gast… #microbiome

Defining transferable microbiota in clinical response to FMT for UC gastrojournal.org/article/S0016-… @WCMC_IBD Gastroenterology Weill Cornell Medicine

The effectiveness of fecal microbiota transplantation (FMT) in treating ulcerative colitis depends on a small set of beneficial bacterial strains, suggests a new study by Dr. Randy Longman of @WCMC_IBD and researchers at #WCM and NewYork-Presbyterian. bit.ly/3mCTpMo

What to do when commenting on Hamas’ terrorist attack against Israel? If your first draft mentions neither the victim nor the perpetrator, rewrite it. If your first draft blames the victim, rewrite it. If you first draft emphasizes “both sides” or empathizes with the