We had a few nice days of cherry blossoms viewing this year.🌸🤩

Excited to share our cryo-ET dataset: 1800+ tomos from 300+lamellae. Huge team work from team Ben Engel, team Max Planck Institute of Biochemistry (MPIB) & my team Microscopy & Spectroscopy + team EMDB - EMPIAR @EBI. We hope resources like this will be useful & push the frontier in cellular structure biology🚀#CryoET

Our manuscript for STOPGAP is now out in Structural Biology! It was great working with Sagar and twitterless Jonathan Wagner. journals.iucr.org/d/issues/2024/…

Lots of updates in #SPACEtomo by Fabian. New target inspection/selection GUI 🖥️🗺️🥳and a video tutorial: youtube.com/watch?v=I5yvi0…

Finally- a book on cryo-electron tomography, written by leading experts! Edited by the one and only Friedrich Forster and myself! link.springer.com/book/10.1007/9…

This is actually democratising cryoEM! Brilliant work by Hari Venugopal Ramaciotti Centre for Cryo EM @GeorgRamm Sub 3 angstrom on a 120 kV technai with a LaB6 source! Read it! It's a masterpiece biorxiv.org/content/10.110…

We present DRGN-AI for fast, ab initio cryo-EM reconstruction! * learns a neural field from unposed images, * designed for single-shot reconstruction of unfiltered datasets, * finds new states missed by prior approaches! Teamwork led by Ellen Zhong drgnai.cs.princeton.edu 1/

This weekend we remembered the life, the science, and the legacy of one of the best women I have had the grace of meeting. We laughed, we cried, we mourned, we gave thanks to her for bringing all of us together

See also: czbiohub.org/life-science/m…

CCP-EM Doppio 1.0.1 released! You can download it for Linux/Mac here... ccpem.ac.uk/download.php

Check out our latest work! 👇We leverage pretrained protein generative models (here Chroma Generate:Biomedicines ) as a prior for inverse problems in protein space (e.g. structure completion, distance contraints, cryo-EM model building). ❄️🏗️ Paper: arxiv.org/abs/2406.04239

We are happy to announce the public release of EMhub, a web platform designed to support the operations of a scientific facility, enabling easy management of users, instruments, bookings, and project tracking. EMhub was unveiled at the #ACA2024 last week by JM de la Rosa Trevin

Structural insight into sodium ion pathway in the bacterial flagellar stator from marine Vibrio | bioRxiv biorxiv.org/content/10.110…

Big congrats to our fearless leader! Well deserved Patrick M Sexton

CryoDRGN-ET❄️🐉 is published in Nature Methods! We combine neural fields and generative modeling to reveal the structural heterogeneity of protein complexes *in situ*! So excited to see this out, and huge congrats to Ramya Rangan, Ryan Feathers and team! nature.com/articles/s4159…

Come and join this amazing group of scientists to work at the cutting edge of structural biology of telomeric complexes. The LMB is a highly collaborative place. Please share!

This is an elegant study showing the differences in structures of hemoglobin in humans and crocodiles which explains why crocs can stay long under water. Very cool 🐊🐊🐊 The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM nature.com/articles/s4146…

#SPACEtomo - a small step towards fast robotic exploration of the vast universe of #cryoET. 🌃🦠❄️🔬 Congrats Fabian !🥳🎉 rdcu.be/dQlI4

SPACEtomo is officially published! :P nature.com/articles/s4159… I'm so grateful for all the support I received especially from Rado Danev and everyone who shared their data with me! And of course thanks to David Mastronarde and the amazing #SerialEM for making it possible!

Molecular architecture of coronavirus double-membrane vesicle pore complex | Nature doi.org/10.1038/s41586…