New paper from the Cingöz Lab, hot off the press! We show that retroviral RNA genomes can be used directly as an mRNA for viral protein production, even in the absence of reverse transcription. nature.com/articles/s4146…

We are rapping today about arrest peptides!! Back-to-back manuscripts in ⁦Nature Communications⁩ showing how RAPP and SecM arrest peptides can stall the ribosome! SecM link here: rdcu.be/dBJTZ nature.com/articles/s4146…

Our structures of RAPP-stalled ribosomes out in ⁦Nature Communications⁩. rdcu.be/dBJTV. Great work by ⁦Martino Morici⁩ and our collaborators ⁦@Pogoscience⁩ ⁦🦋 Sara Gabrielli⁩ for MD and Shinobu Chiba lab for great biochemistry! Data from ⁦CEITEC⁩

@ #DPG2024 spring meeting in the fantastic #Berlin. Yesterday, I gave a talk on RNA adsorption onto membranous surfaces, the discussion after a lipid-rich session was very active, and tackled novel challenging aspects, more to come #RNA #compchem #lipidRichDiscussions

Excellent and comprehensive review on co-transcriptional gene regulation both in eukaryotes and prokaryotes! By @NeugebauerKarla and Herzel lab Lydia Herzel, AG Herzel, RNA Dynamics nature.com/articles/s4158…

Excited to be moving on to the Elite 8 in #STATMadness STAT! Thanks again to everyone who voted for us & please continue to support UCSC in the search for best innovation in science & medicine thanks! voting link: statnews.com/feature/stat-m… our RNA liquid biopsy technology:

I've been told I need to 'tweet'? X? So... a countdown of highlights for you: 6 PhD students, 4 postdocs, 4 undergrads, 3 NOAs, 3 manuscripts under review, 1 paper accepted, and a summer program for high school students. Not bad for a year and three months of PI life :D

First symposium for the #Krahnlab!🥳Proud of my graduate students antavius cain and Joshua Weiss for presenting their work and future plans at the #SERCAT symposium UGA

Cellular repair of DNA breaks enables editing of the human genome. Do human cells repair RNA breaks, and can we use it to edit transcriptomes? Our work with Anna Nemudraia and Wiedenheft Lab is now online in Science Magazine! #ScienceResearch science.org/doi/10.1126/sc…

New paper! We provide a scRNA-seq pipeline for simultaneous gene expression and 3′UTR length analysis. We quantified 3′UTRs in 474 cell types and found that 3′UTR length provides information that is independent of gene expression. nature.com/articles/s4146…

What does the RNA binding surface of PRC2 actually do? We show that part of the RNA binding surface is required for PRC2 function through interactions with nucleosomes, but we find no evidence that RNA is in play. nature.com/articles/s4158…

We are incredibly excited to have our first LncRNA screening paper published today in pnas . This project has been a labor of love for over 8years!! LncRNAs are tricky to tease apart mechanistically! Here we provide a resource of LncRNAs involved in macrophage differentiation

Amazing talk by Jeanine Gezelle at #RNA2024. she presented her work on a new viral exoribonuclease-resistant RNA structure. Preprint coming soon! #proudPI

Now officially published nature . Led by the one and only Yaara Finkel. By engineering HCMV to express sgRNA libraries directly from the viral genome, we developed VECOS (Virus Encoded CRISPR-based direct readOut System).

In our new review paper, Yue Wan and I focused on the functional importance of RNA structure in gene regulation. Many thanks to Yue and Xinang! I really enjoy the writing process. nature.com/articles/s4158…

Thrilled to finally have our paper examining Neisseria gonorrhoeae-neutrophil transcriptional responses by dual RNAseq out today with PLOS Pathogens! A brief 🧵: journals.plos.org/plospathogens/…

How are thousands of transcripts are localised within the cells? Happy to share my review on RNA localization Nature Cell Biology #RNA nature.com/articles/s4155…

For anyone interested in RNA and cancer (basic and translational research), please consider submitting an abstract for this exciting meeting! We will be choosing lots of talks from abstracts. Should be a great event! #aacrRNA24

promoted to Professor😀Many thanks to the current and previous lab members🙏I am super grateful for having great collaborators through the years🙏And many thanks to all the friends who have been supporting me and my lab in the past 10 years! Thank you all🙏❤️❤️❤️