Early cancer vaccine data breathe new life into the field, but many questions remain.

My story for Endpoints News rounds up some new data disclosures at #AACR24 and explains why researchers are hopeful that cancer vaccines might finally work.
endpts.com/early-cancer-v…

Reporting for Endpoints News from #AACR2024 , it's a packed house!

FDA greenlights first test of gene editing therapy in babies from Jim Wilson startup iECURE. Read more in my story for Endpoints - endpts.com/fda-greenlight…

Looking forward to interviewing Arena BioWorks cofounder Stuart Schreiber this morning as part of Endpoints News Drug Discovery Day. The event starts at 10, and my fireside chat with Dr. Schreiber begins at 10:50. If you haven't signed up already, do it now! events.endpts.com/drugday24

SCOOP: A stealth startup has big plans in obesity and $350M to back it, Endpoints has learned

Metsera is led by former Medicines Co. CEO Clive Meanwell w/ backing from ARCH, GV, F-Prime, Mubadala, Newpath, SoftBank, ADIA, & more.

$, pipeline details:
endpts.com/new-obesity-bi…

After selling Prometheus Bio to Merck for $10.8 billion last year, Mark McKenna has raised a $400 million Series A for a sequel company going all in on 'precision immunology'

Read more in my story for Endpoints News:

endpts.com/former-prometh…

A new preprint from David Baker’s lab Institute for Protein Design shows that generative AI can design antibodies. But are they good enough to become drugs?

Not yet, at least not at the touch of a button. Read more in my story for Endpoints News:

endpts.com/david-bakers-l…

Labcorp expands #Alzheimers blood tests for doctors and drugmakers, with a $227 test for a form of #tau protein (pTau217) that's indicative of #amyloid pathology in the brain and could help identify patents for follow up. More in my story for Endpoints News

endpts.com/labcorp-expand…

A long-awaited Phase 3 study of a #tuberculosis #vaccine is finally underway, 5.5 years after promising Phase 2 results wowed researchers in the field. The Bill & Melinda Gates Medical Research Institute licensed the vax from GSK. More details in my story for Endpoints News:

endpts.com/gates-backed-p…

🏆I'm thrilled that Endpoints News has won SABEW's general excellence award for our coverage of the biopharma and healthcare businesses. It's a testament to the power of this hard-working newsroom and all they achieved in 2023!

Some very exciting, but very early, studies this week suggest that CAR-T cell therapies can help shrink aggressive brain tumors.

Endpoints News first reported this back in November when preliminary results were announced at a medical meeting.

Read more here: endpts.com/car-t-cell-the…

“If this happens, this will create chaos within the system ... It could potentially drive some biotech companies out of business.”

A must-read story from Jared Whitlock on the implications of a potential US crackdown on drugmakers working with WuXi:

endpts.com/wuxi-became-a-…

The FDA's eleventh-hour call for an advisory committee raised many questions about Lilly's Alzheimer's drug #donanemab . Zach Brennan and I outline the topics that will drive debate over donanemab + Leqembi in the months to come. Our story for Endpoints News

endpts.com/five-questions…

David Baker's Institute for Protein Design group has a new 'all atom' versions of his #AI tools RoseTTAFold and RFdiffusion for #protein structure prediction and design.

'We’re releasing everything, including the code,' he told me. More in my story for Endpoints News
endpts.com/david-bakers-l…

Amylyx's ALS treatment Relyvrio fails PhIII study, biotech to consider withdrawing drug - Max Gelman and Andrew Dunn have the story for Endpoints News endpts.com/amylyxs-als-tr…

New: FDA again delays approval decision on Eli Lilly’s Alzheimer’s drug donanemab, calls for advisory committee

Ryan Cross the Science Boss reports Endpoints News

endpts.com/fda-delays-dec…

Who's going to AACR in San Diego next month? Have cool science on targets or technologies for treating #cancer ? Get in touch with Lei Lei Wu and I, we will be there reporting for Endpoints News. #AACR24

As Amylyx prepares for its pivotal ALS drug readout, it hopes to settle questions about efficacy. Story w/Andrew Dunn

endpts.com/amylyx-readies…

Today at Endpoints News we're kicking of our call for nominations for our annual LGBTQ+ leaders list.

I'm thrilled that Kyle LaHucik leads this for us, and I can't wait to continue to grow this project and make it bigger and better in the years to come.

endpts.com/whos-paving-th…

When Chan Zuckerberg @CZI opened up applications for a new Chan Zuckerberg Biohub Network, it was overwhelmed with responses. After opening two Biohubs last year, now it is funding four regional projects to probe the mysteries of RNA and protein networks in cells. Endpoints News

endpts.com/chan-zuckerber…