elizabeth bennett This past year+, I became afraid of mob mentality. I'd never really experienced it like this before, but now I see very clearly how things have gone sideways throughout history. Once it gets going there seems to be very few things that can change the course before it's too late.

Does anyone else find it annoying that Twitter removes people from your list of follows and you only find out when you stumble on them again and see the unhighlighted 'follow'? How/why is this happening?

Kneel and disconnect And waste another year m.youtube.com/watch?v=7f5OTV…

How long is too long to gaze into the abyss? Resolution always seems farther away the more I look.

Dr. Lynora Saxinger MD FRCPC Infectious Diseases No. This risk was apparent almost 2 years ago, and pandemic policy must be held accountable for the contribution to this problem. No sweeping under the rug! nature.com/articles/d4158…

Ebony Jade Hilton, MD @TrishtheDish_7 Nick Foy Pre-covid, the best evidence we had (systematic reviews of RCTs) got us, at best, 'we don't know'. Cochrane review of such (to November 2020): cochranelibrary.com/cdsr/doi/10.10… Conditions for equipoise are met, and running an RCT is perfectly ethical in this case (we did 2 for covid btw)

Ebony Jade Hilton, MD @TrishtheDish_7 Nick Foy From Cochrane's systematic review of RCTs:

Ebony Jade Hilton, MD @TrishtheDish_7 Nick Foy DANMASK was the first RCT on masking specific to covid, could not find statistical significance (it was underpowered, designed to identify >50% effect size and it did not) doi.org/10.7326/M20-68…

Ebony Jade Hilton, MD @TrishtheDish_7 Nick Foy The Bangladesh cluster randomized trial was the biggest (~342,000 participants, and probably best study we have on this. science.org/doi/10.1126/sc… Cloth masks had no effect. Surgical had ~10% effect, but oddly was only significant for those aged 50-70.

Ebony Jade Hilton, MD @TrishtheDish_7 Nick Foy This one was also re-analyzed for bias here: trialsjournal.biomedcentral.com/articles/10.11…

Clifton Duncan Watching this poor man slowly and methodically unfurl a deep betrayal from his own profession over the past 2.5 years was quite a thing to see.

Reading this, and the comments, I wonder how it's possible to even be from the same planet. There are different worlds out there, somehow occupying the same space.

JB Kevin Bass PhD MS CFR is a function of testing, and when testing isn't random (only hosp. for eg.) it wildly overestimates as a proxy for IFR, missing mild cases (denominator) while catching most severe cases/deaths (numerator). Add in sensitive pcr testing and numerator also contains incidentals

JB Kevin Bass PhD MS Better: random testing, for something longer lasting (antibodies) to est. the true number of infections (seroprevalence). Then stratify by risk factors like age Here's what you get when you do that. Paper from Nov. 2020 More useful info for policy nature.com/articles/s4158…

Why not just move on to better interventions? This one sucks, a lot, and is not worth wasting any more energy on. I will admit there is a hypothetical chance they are better than nothing, but it's debatable and they virtually always fail the trials no matter what the design is.

Replies blocked of course. This is in reference to a mask study showing surgical non-inferior to N95. Besides some doctors now becoming theor own brand of conspiracy theorists like this, these hypocrites seem to didn't mind at all Pfizer trying to bury their data for 75 years.

calgary.citynews.ca/2025/01/16/can…