Excited to share the news that I have been awarded a 3-year ACED Project Award with my co-leads, Young Hwan Young Hwan Chang and Marnix @janson_marnix . Together, we will look at why intestinal metaplasia could occur in both oesophagus and stomach, their similarities and differences

Huge congratulations to John Lizhe Zhuang and collaborators Marnix Jansen and Young Hwan Chang on their #ACEDearlydetection Project Award. The team will investigate what drives intestinal reprogramming in stomach and oesophageal #Cancers OHSU Knight Cancer Institute UCL Cancer Institute

COEXIST: Coordinated single-cell integration of serial multiplexed tissue images biorxiv.org/content/10.110…

Excited to have had the opportunity to present alongside excellent researchers on applications of mechanistic modeling and data science at #SIAMLS24! Big thank you to the minisymposium organizers John Metzcar Paul Macklin and Sarah Bruningk

UniFORM: Towards Universal Immunofluorescence Normalization for Multiplex Tissue Imaging biorxiv.org/content/10.110…

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon febs.onlinelibrary.wiley.com/doi/full/10.10…

Our new paper is out, and zac will be presenting it at #GTC next week. Language of Stains: Tokenization Enhances Multiplex Immunofluorescence and Histology Image Synthesis biorxiv.org/content/10.110…

Our recent work "Learning a Language of Stains" was presented as a poster at NVIDIA GTC 2025 nvidia.com/gtc/posters/?s…

These speakers from OHSU News will focus on cutting-edge research that is using #AI and #MachineLearning techniques to advance our knowledge of both diagnostics and mechanisms that drive disease! See the full #Pathobiology2025 program bit.ly/3yOeuxu

Automated Quality Control of Time-Course Imaging from 3D in vitro cultures biorxiv.org/content/10.110… #biorxiv_bioeng

Congrats Eun-Na! We found that inflammation patterns in artery disease (AAA) differ based on CRP protein deposits. Multiplex tissue imaging showed how immune cells change, pointing to new treatment ideas. doi.org/10.1016/j.trsl…

Really excited to share our new Cell Press Cell paper with Elana Fertig and colleagues. 1/n cell.com/cell/fulltext/… National Cancer Institute NIH JKTG Foundation Mathoncoblog SMB - Society for Mathematical Biology IU Bloomington IU Luddy The Breast Cancer Research Foundation

COEXIST — a new algorithm to align serial multiplex tissue imaging (MTI) sections at single-cell resolution. By integrating spatial + molecular features, COEXIST overcomes biological heterogeneity to unlock deeper insights into the tumor microenvironment. doi.org/10.1371/journa…

Multiplex tissue imaging needs robust normalization. UniFORM preserves biological signals while correcting batch effects—feature- and pixel-level, platform-agnostic, Python-based: doi.org/10.1016/j.crme…

Exciting news! 🎉 Our invention, “Translation of images of stained biological material,” has been issued. AI turns routine stains (H&E) into virtual specialized stains → faster, more accessible tissue analysis. patents.google.com/patent/US12327…

Excited to be at #MICCAI2025 next week! 🎉 With Zachary Sims, we’ll present “Language of Stains: Tokenization Enhances Multiplex Immunofluorescence and Histology Image Synthesis” 👉 link.springer.com/chapter/10.100… Let’s connect if you’re there!

Looking forward to the Vanderbilt Symposium on AI + Spatial Systems Biology 2025 next week! I will be presenting our recent advances in this space. vanderbilt.edu/computational-…

Excited to speak this weekend at the Vanderbilt Symposium on #AI, #Spatial & Systems Biology 2025—hosted by Ken Lau Lab and Tae Hyun Hwang at Vanderbilt University’s Center for Computational Systems Biology. 🌟A stellar speaker lineup! Agenda: vanderbilt.edu/computational-… Onsite full—join virtually