Big research news today! @AngiomaAlliance nih.gov/news-events/ne…

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism From labs of Douglas A. Marchuk & Mark L. Kahn. nature.com/articles/s4158…

We are hiring! #Postdoc position available for a collaborative project with Pumiglia_Lab. Identifying functional impact of #Vascular risk genes for #AlzheimersDisease please RT! Capital District Postdoc Association @AlbanyMedDNET CapSciNY OSSD #ENDALZ #ExpBio #WiN

Correlation Vs. Causation

Meanwhile in the home-lab, the latest batch of Chevre from our "herd" is draining!

This is not right. @NIHDirector Dr. Kimryn Rathmell , National Cancer Institute these are exactly the type of scientists we should be supporting now. Women, especially young mothers, are dropping out of science at alarming rates. I am getting desperate messages from women all over the world. We must help

No, it’s not a gummy bear come-to-life. This creepy-crawly creature is actually a human #fibroblast cell. A recent #NIDCR study found fibroblasts migrate using a ‘front wheel drive’ mode. Learn how the results could shed light on thwarting #cancer spread: go.usa.gov/xHvdh

Respect to researchers that use 3D electron microscopy. We took our first dip into this amazing technology and were humbled by the work involved. But the results were amazing! See how pericytes of brain capillaries dig their "claws" into endothelial cells. journals.sagepub.com/doi/full/10.11…

"grad student" is easier to say than "scientist/lab technician/data analyst/grant- and manuscript-writer/copy editor/project manager/software engineer/graphic designer/teacher/exam-grader/amateur mouse rancher and veterinarian" but somehow feels a lot less accurate

Amy Kimble and summer student Jordan Silva led an effort to isolate endothelial nuclei from archived frozen brain tissue to allow us to begin to interrogate RNA splicing in the #BBB

Returned to Michigan Medicine to check in with my oldest significant experiment, started in Ann Arbor about 26 years ago. I am really proud of the result.

It’s time to change this slide! FDA approval today of #sotorasib. Congrats @JonathanOstrem & Ulf Peters on launching the successful attack with tethering from Jim Wells and scientists at Wellspring! Many steps-great to see the summit reached!! UCSF Helen Diller Family Comprehensive Cancer Ctr HHMI

This always feels good...it seemed to be safely below payline but nearly 5 months since council. Thought NIH was changing their mind. They did quite a hack job on the budget considering it was modular - hopefully it went to fund somebody else!

The endothelium puts a brake to cytokine signaling to prevent endotheliopathy and multiorgan dysfunction. Want to learn more? Nina’s paper is out as an in-press preview JCI insight! Thank you to all the amazing collaborators at Albany Med MCP 🧫🔬🧬! insight.jci.org/articles/view/… 👇📜

Grant awarded! So excited to work on this U01 on impact of #Alzheimers risk genes on neurovascular interactions with Sally Temple Regenerative Research Fdn/NSCI Celeste Karch Oscar Harari Test Account Martin Kampmann and Pumiglia_Lab Albany Med Health System. Thank you N/A! #EndAlz

Congratulations!

She’s finally here! Meet our new postdoc Dr Kasey Belanger-Mayer! She joined us from Jen Sullivan’s lab MCG. Kasey will be working with us and Pumiglia_Lab on a collaboration identifying neurovascular interactions of AD risk genes. #EndAlz @AlbanyMedDNET