Carlos Puig Jové (@puigjove) 's Twitter Profile
Carlos Puig Jové

@puigjove

#Endocrinologist MD PhD, currently at @EndoNutMutua, lipid unit @Mutua_Terrassa. Particular interest in diabetes, adiposity and lipids. Professor @UICBarcelona.

ID: 1122823271261581312

linkhttps://orcid.org/0000-0001-9466-2627 calendar_today29-04-2019 11:21:43

486 Tweet

622 Followers

669 Following

National Lipid Association (@nationallipid) 's Twitter Profile Photo

📉Lower LDL-C for longer is better. The NLA’s new guidance simplifies LDL-C management for adults — helping clinicians & patients improve evidence-based measurement and treatment of LDL-C. Read the guidelines & recommendations: lipidjournal.com/article/S1933-…. Beth Jackson Christie Ballantyne

📉Lower LDL-C for longer is better.

The NLA’s new guidance simplifies LDL-C management for adults — helping clinicians & patients improve evidence-based measurement and treatment of LDL-C.

Read the guidelines &amp; recommendations: lipidjournal.com/article/S1933-…. <a href="/LipidCNS/">Beth Jackson</a> <a href="/CBallantyneMD/">Christie Ballantyne</a>
Marcos Gamboa (@markinho_gc) 's Twitter Profile Photo

🔰Ecogenicidad de las placas carotídeas como predictor de regresión tras la terapia hipolipemiante.🇨🇳 ✅️ 838 pacientes con placas carotídeas que recibían terapia hipolipemiante se inscribieron entre julio de 2020 y mayo de 2024 y fueron seguidos durante 12 meses. ✅️Las

🔰Ecogenicidad de las placas carotídeas como predictor de regresión tras la terapia hipolipemiante.🇨🇳

✅️ 838 pacientes con placas carotídeas que recibían terapia hipolipemiante se inscribieron entre julio de 2020 y mayo de 2024 y fueron seguidos durante 12 meses.

✅️Las
Gonzalo Perez (@gonzaeperez) 's Twitter Profile Photo

TERAPIA HIPOLIPEMIANTE COMBINADA EN PACIENTES DE ALTO RIESGO CARDIOVASCULAR 🫀 Parece una estrategia más razonable 🧐 Terapia combinada 🆚 estatinas en altas dosis -Mayor ⬇️ de LDL-c -Mayor ⬇️de eventos CV -Menor suspensión o ⬇️ de dosis Vía European Society of Cardiology Journals academic.oup.com/cardiovascres/…

TERAPIA HIPOLIPEMIANTE COMBINADA EN PACIENTES DE ALTO RIESGO CARDIOVASCULAR 🫀
Parece una estrategia más razonable 🧐
Terapia combinada 🆚 estatinas en altas dosis
-Mayor ⬇️ de LDL-c
-Mayor ⬇️de eventos CV
-Menor suspensión o ⬇️ de dosis
Vía <a href="/ESC_Journals/">European Society of Cardiology Journals</a>
academic.oup.com/cardiovascres/…
Manuel Botana 🇪🇸 (@mbotana) 's Twitter Profile Photo

La diabetes gestacional representa un marcador de salud Cardiovascular previo al embarazo y enfatiza la importancia de mejorarla precozmente antes del embarazo - Prepregnancy Cardiovascular Health, Gestational Diabetes, and Coronary Artery Calcium jamanetwork.com/journals/jamac…

Pablo Corral MD (@drpablocorral) 's Twitter Profile Photo

A must-read in the field of cardiovascular prevention: “Residual cardiovascular risk beyond LDL-C: inflammation, remnant cholesterol, and lipoprotein(a)” by Anders Wulff and Prof. Børge Nordestgaard, just published in the European Heart Journal (2025). This editorial

A must-read in the field of cardiovascular prevention:

“Residual cardiovascular risk beyond LDL-C: inflammation, remnant cholesterol, and lipoprotein(a)” 
by Anders Wulff and Prof. Børge Nordestgaard, just published in the European Heart Journal (2025).

This editorial
Sociedad SEEN (@sociedadseen) 's Twitter Profile Photo

🗣️Orticumab: the potential to harness oxidized LDL to reduce coronary inflammation with plaque-targeted therapy ▶️El tratamiento con orticumab representa una forma nueva y específica de reducir la inflamación arterial journals.lww.com/co-lipidology/… LipidoSEEN

🗣️Orticumab: the potential to harness oxidized LDL to reduce coronary inflammation with plaque-targeted therapy

▶️El tratamiento con orticumab representa una forma nueva y específica de reducir la inflamación arterial

journals.lww.com/co-lipidology/…
<a href="/LipidoSeen/">LipidoSEEN</a>
Pablo Corral MD (@drpablocorral) 's Twitter Profile Photo

🤔If high LDL cholesterol is so dangerous… why doesn’t it hurt? ☝️Because evolution doesn’t care if you drop dead after you’ve reproduced. 👉LDL cholesterol is a silent killer—causal, cumulative, and completely asymptomatic. You won’t feel your arteries clogging. You won’t

🤔If high LDL cholesterol is so dangerous… why doesn’t it hurt?

☝️Because evolution doesn’t care if you drop dead after you’ve reproduced.

👉LDL cholesterol is a silent killer—causal, cumulative, and completely asymptomatic. 
You won’t feel your arteries clogging. You won’t
Marcos Gamboa (@markinho_gc) 's Twitter Profile Photo

🔰Una ecuación de Sampson-NIH modificada con mayor precisión para estimar niveles bajos de C-LDL. 👏Que gran trabajo de Rafael Zubirán y sus colegas, utilizando los resultados de las pruebas del panel lipídico de la Clínica Mayo y el ensayo clínico FOURIER, realizaron una ecuación

🔰Una ecuación de Sampson-NIH modificada con mayor precisión para estimar niveles bajos de C-LDL. 

👏Que gran trabajo de <a href="/RZubiranS/">Rafael Zubirán</a> y sus colegas, utilizando los resultados de las pruebas del panel lipídico de la Clínica Mayo y el ensayo clínico FOURIER, realizaron una ecuación
Cristina Tejera (@cristinatejerap) 's Twitter Profile Photo

⭐️¿Y si una molécula producida por tu microbiota intestinal pudiera causar aterosclerosis sin alterar el colesterol? Eso sugiere un nuevo estudio en Nature 👇 🔗 nature.com/articles/s4158… Investigadores identifican el imidazol propionato (ImP) como un metabolito microbiano

LipidoSEEN (@lipidoseen) 's Twitter Profile Photo

🔬 Nuevo análisis del FOURIER trial comentado por el Dr. Gimeno-Orna: 👉 En pacientes con ECV y EAI, la reducción intensiva de cLDL con iPCSK9 aporta mayor beneficio relativo y absoluto. ✅ Refuerza la sinergia entre inflamación e hiperlipemia. 👉 seen.es/blog/lipidos-y…

🔬 Nuevo análisis del FOURIER trial comentado por el Dr. Gimeno-Orna:

👉 En pacientes con ECV y EAI, la reducción intensiva de cLDL con iPCSK9 aporta mayor beneficio relativo y absoluto.

✅ Refuerza la sinergia entre inflamación e hiperlipemia.
👉 seen.es/blog/lipidos-y…
Scott Isaacs (@scottisaacsmd) 's Twitter Profile Photo

The BMI is a marker of total body mass and not a specific marker of adipose tissue mass. Relative fat mass #RFM is an alternative to BMI with superior performance of RFM in assessing cardiometabolic risk. nature.com/articles/s4157…

The BMI is a marker of total body mass and not a specific marker of adipose tissue mass. Relative fat mass #RFM is an alternative to BMI with superior performance of RFM in assessing cardiometabolic risk.
nature.com/articles/s4157…
Alfonso Valle (@vallealfonso) 's Twitter Profile Photo

🔴🔴Lilly's Mounjaro (tirzepatide), a GIP/GLP-1 dual agonist, demonstrated CV protection in patients with type 2 diabetes and heart disease 👍Mounjaro met the primary objective of non-inferiority vs. Trulicity with an 8% lower rate of MACE-3 events, while delivering greater

🔴🔴Lilly's Mounjaro (tirzepatide), a GIP/GLP-1 dual agonist, demonstrated CV protection in patients with type 2 diabetes and heart disease

👍Mounjaro met the primary objective of non-inferiority vs. Trulicity with an 8% lower rate of MACE-3 events, while delivering greater
Pablo Corral MD (@drpablocorral) 's Twitter Profile Photo

👉Cholesterol Crystals: Not Just a Marker — A Causal Trigger of Vascular Inflammation ☝️A growing body of evidence highlights cholesterol crystals (CCs) as active drivers—not mere bystanders—in the pathogenesis of atherosclerosis. ☝️CCs initiate a cascade of inflammatory events

👉Cholesterol Crystals: Not Just a Marker — A Causal Trigger of Vascular Inflammation

☝️A growing body of evidence highlights cholesterol crystals (CCs) as active drivers—not mere bystanders—in the pathogenesis of atherosclerosis.

☝️CCs initiate a cascade of inflammatory events
Sociedad SEEN (@sociedadseen) 's Twitter Profile Photo

📕Can small dense LDL cholesterol be estimated from the lipid profile? 👉La estimación del c-LDLd estimado presenta una alternativa prometedora a la medición directa journals.lww.com/co-lipidology/… LipidoSEEN

📕Can small dense LDL cholesterol be estimated from the lipid profile?

👉La estimación del c-LDLd estimado presenta una alternativa prometedora a la medición directa

journals.lww.com/co-lipidology/…
<a href="/LipidoSeen/">LipidoSEEN</a>
Dr Alo, DO, FACC (@mohammedalo) 's Twitter Profile Photo

Lp(a) as a Prognostic Marker of ASCVD Progression New study with 460k participants showed that: 1️⃣ Median Lp(a) Levels: 1) No Vascular Disease: 19.5 nmol/L 2) Incident PAD: 25.3 nmol/L 3) PAD to MALE: 33.3 nmol/L 4) Incident Carotid Stenosis: 29.5 nmol/L 5) Carotid Stenosis to

Lp(a) as a Prognostic Marker of ASCVD Progression

New study with 460k participants showed that:

1️⃣ Median Lp(a) Levels:

1) No Vascular Disease: 19.5 nmol/L
2) Incident PAD: 25.3 nmol/L
3) PAD to MALE: 33.3 nmol/L
4) Incident Carotid Stenosis: 29.5 nmol/L
5) Carotid Stenosis to
Dr Alo, DO, FACC (@mohammedalo) 's Twitter Profile Photo

Promising Drugs For Lp(a) Reduction Five drugs in development that lower Lp(a) concentrations by 65-98%: 1️⃣ Muvalaplin: 65% 2️⃣ Pelacarsen: 80% 3️⃣ Olpasiran: 98% 4️⃣ Zerlasiran: 98% 5️⃣ Lepodisiran: 98% Thomas Dayspring Dr. Spencer Nadolsky Karl Nadolsky Gil Carvalho MD PhD🌈🇵🇸 Matthew Nagra, ND

Promising Drugs For Lp(a) Reduction

Five drugs in development that lower Lp(a) concentrations by 65-98%:

1️⃣ Muvalaplin: 65%
2️⃣ Pelacarsen: 80%
3️⃣ Olpasiran: 98%
4️⃣ Zerlasiran: 98%
5️⃣ Lepodisiran: 98%

<a href="/Drlipid/">Thomas Dayspring</a> <a href="/DrNadolsky/">Dr. Spencer Nadolsky</a> <a href="/DrKarlNadolsky/">Karl Nadolsky</a> <a href="/NutritionMadeS3/">Gil Carvalho MD PhD🌈🇵🇸</a> <a href="/drmatthewnagra/">Matthew Nagra, ND</a>
Maxima Mendez,MD.FACC (@maximamendez15) 's Twitter Profile Photo

Lipoprotein(a) Doesn’t Budge: New Atherosclerosis study (Koller et al., 2025) shows Lp(a) levels stay remarkably stable over 3.2 yrs. -✅ 91.6% stayed in same risk category -⚠️ Variability mostly due to lab error, not biology Link➡️ atherosclerosis-journal.com/action/showPdf… European Atherosclerosis Society

Lipoprotein(a) Doesn’t Budge: 
New Atherosclerosis study (Koller et al., 2025) shows Lp(a) levels stay remarkably stable over 3.2 yrs.

-✅ 91.6% stayed in same risk category
-⚠️ Variability mostly due to lab error, not biology 

Link➡️ atherosclerosis-journal.com/action/showPdf…

<a href="/society_eas/">European Atherosclerosis Society</a>
NEJM (@nejm) 's Twitter Profile Photo

CONFIDENCE trial: In persons with chronic kidney disease and type 2 diabetes, combination therapy with finerenone and empagliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either drug alone. Full trial results and Research Summary:

CONFIDENCE trial: In persons with chronic kidney disease and type 2 diabetes, combination therapy with finerenone and empagliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either drug alone. Full trial results and Research Summary:
Manuel Botana 🇪🇸 (@mbotana) 's Twitter Profile Photo

Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity | New England Journal of Medicine nejm.org/do/10.1056/NEJ…