We are looking to fill a postdoctoral position PrudencioLab to work on TDP-43 in the area of RNA splicing regulation. …wp-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candidat…

I’m super duper excited to share our latest preprint!!! Here, we used iPSC models to show that tau mutations cause broad defects in microglia. ⁦@WUADRC⁩ ⁦The Rainwater Charitable Foundation⁩ ⁦CurePSP⁩ ⁦WashU Center of Reg Med⁩ ⁦WashU Office of Neuroscience Research⁩ ⁩ ⁦CZI Science⁩ medrxiv.org/content/10.110…

Several MBI members were recognized at UF Medicine's spring faculty assembly, including Dr. David Borchelt (Lifetime Achievement Award, pictured below) and Dr. Maryam Rahman (collegewide Clinical Excellence Award). See the full list of recipients here 👉 bit.ly/3KsjaeI

📣 Meet our newest grant recipients across Alzheimer’s disease, macular degeneration, and glaucoma research! These 44 exceptional investigators, selected for their potential to bring us closer to cures by pursuing the untried, the unexpected, and the most promising ideas,

science.brightfocus.org/individual/mer… Thanks Brighfocus for this great award!

Milestone Achieved: Target Identification Target ALS-funded consortia discovered HDGFL2 cryptic peptide, a potential biomarker found when TDP-43 is dysfunctional—a key factor in 97% of #ALS cases. This could revolutionize diagnosis and treatment. 🔗 bit.ly/3Td6yN2

🎉Thrilled to share our new paper ⁦Science Advances⁩ led by first author Dr. Yunjung Jin! Big thanks to all our amazing collaborators! ⁦@owenaross⁩ Shunsuke Koga⁩ ⁦Dr. Pam McLean⁩ ⁦Tsuneya Ikezu⁩ ⁦⁦Mayo Clinic Neuro⁩ ⁦ science.org/doi/10.1126/sc…

Excited to finally publish our work on cryptic splicing in Perry syndrome. Moreover, it higlights that not all cryptic RNAs are detected in every brain region with TDP-43 pathology. Enjoy! PrudencioLab …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

Very proud of this new study from the lab! 🌟We identified a novel lncRNA, FAM151B-DT, that is disrupted across neurodegenerative diseases. medrxiv.org/content/10.110…

A novel lncRNA FAM151B-DT regulates autophagy and degradation of aggregation prone proteins: medrxiv.org/content/10.110…

I joined the Prudencio lab at Mayo’s Department of Neuroscience as a Research Fellow last month! So exciting to be working on great science with this great group of ladies. #STEM #Neuroscience #TDP #TDP43 #proteostasis #proteinopathy #proteopathy

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes: nature.com/articles/s4146…

Our manuscript got highlighted with a beautiful infographic! #TDP43 #PerrySyndrome #Neurodegeneration #RNAsplicing #Biomarkers #Neuroscience #FTLD #ALS PrudencioLab DOI: doi.org/10.1002/mds.30…

I was thrilled for the opportunity to present today at #ADPD2025 the work PrudencioLab, in the wonderful city of Vienna where I was lucky to get an awesome tour by Dr Wilfried Rossoll!

When #DanDoctoroff was diagnosed with #ALS, he saw an opportunity to make change. See what inspired him to found Target ALS to accelerate the discovery, development, and path to effective treatments. Take action today: targetals.org/take-action/ #ALSResearch #EveryoneLives

C9ORF72 poly-PR disrupts expression of ALS/FTD-implicated STMN2 through SRSF7 actaneurocomms.biomedcentral.com/articles/10.11…

Join us in celebrating our 2024 Cozzarelli Prize Class IV: Biomedical Sciences winning paper, “Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis.” Read more: ow.ly/SyAL50VyXLV

mdpi.com/1422-0067/26/1…