DSP risk score is out! Check it out here: dsp-risk.com Well done Alessio Gasperetti, MD PhD and team!

#5 Bad Advice: Stop trying to innovate and just learn to work within the system. I was told early on that medicine was not a career for innovation - instead, tradition and incrementalism is the way forward. Incrementalism (where small improvements happen over time) is the

European Society of Cardiology Journals EJPC Editor-in-Chief EAPCPresident Great review! Low voltage QRS quite common in PLN R14del cardiomyopathy (appr. 30% of asymptomatic individuals, -50% of symptomatic G+). PLN R14del has been identified in > 15 countries from 4 different continents so far.

And the 2024 #atrialfibrillation #ESCGuidelines are OUT!!!! academic.oup.com/eurheartj/arti… Access all GLs at: escardio.org/Guidelines/Cli… #ESCCongress #EHRA_ESC European Society of Cardiology EHRAPresident

Well done to Alessio Gasperetti, MD PhD and colleagues for putting the largest DSP cohort together! DSP cardiomyopathy is increasingly recognized as a separate clinical entity and marks the significance of the gene-first approach in cardiomyopathies. academic.oup.com/eurheartj/arti…

In 2019, our hypertrophic cardiomyopathy gene curation showed 2/3 of "HCM" genes had ltd/no evidence, with 8 sarcomere genes being key We are excited to share the ClinGen HCM re-appraisal > with 29 genes to be included! medrxiv.org/content/10.110…

Delighted to contribute to this new work published last week in Nature Genetics on disease prediction. If our aim is to empower prevention of disease by producing the most powerful and accurate prediction tools then it makes sense to explore any and all data that might be

This year’s chemistry laureates Demis Hassabis and John Jumper have developed an AI model, AlphaFold2, to solve a 50-year-old problem: predicting proteins’ complex structures. Check out two examples of protein structures determined using AlphaFold2. First up, a bacterial enzyme

Some ideas seem silly, until they’re not!

A great day for anyone attending! Many thanks to Y Combinator for the opportunity. Enlinked Zafeirenia Xylouri

We need to overhaul how we fund, conduct and communicate scientific research.

Excited to share the state of the art review on “Naxos Disease and Related Cardio-Cutaneous Syndromes”. Well done to Adalena Tsatsopoulou for leading this effort. sciencedirect.com/science/articl…

Sunday is a perfect day to get your free registration and think about the clinical cases to submit to our Hereditary Cardiovascular Diseases course March 20-22, 2025. Link in comment Dimitra Antonakaki Antoine Bondue Elena Arbelo Alex Protonotarios Juan Pablo Kaski iacopo olivotto Prof Michael Papadakis

Paperwork isn’t work - the robots can have it.

x.com/i/grok/share/7… Just tried the DeepSearch that the new Grok 3 does and asked a question that is exremely niche: "what is the performance of the arvc risk calculator for PKP2 patients". I know it is niche because this information is conveyed in the supplementray material

What a fabulous first day for our 9th edition of the Hereditary Cardiovascular Diseases Course! Thank you to all the fantastic speakers, and see you all today at noon (CET time)! Elena Arbelo iacopo olivotto Alex Protonotarios Bogdan A. Popescu Roberto Barriales-Villa Pablo Garcia-Pavia Kristina Haugaa

An introvert with AI can do wonders.

Context engineering is an abstracted way to describe how to guide intelligent beings’ behaviour. It has significant parallels to what we call education (in humans).

Prognostic Role of Myocarditis-Like Episodes and Their Treatment in Patients With Pathogenic Desmoplakin Variants | Circulation ahajournals.org/doi/10.1161/CI…