PfanderLab (@pfanderlab) 's Twitter Profile
PfanderLab

@pfanderlab

Discovery Science in the Genome Integrity field. Opinions are our own.

ID: 1438398729069989890

linkhttps://ccb.tu-dortmund.de/en/professorships/dolce-dortmund-life-science-center/pfander/ calendar_today16-09-2021 07:06:08

247 Tweet

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Jan Kosinski (@jankosinski) 's Twitter Profile Photo

AlphaFold3 is insane. MutS protein (green) recognizes base mismatches in DNA (gray), after which it slides off to find MutL matchmaker protein (blue), which positions and activates MutH nuclease (pink) to nick a hemimethylated GATC sequence (red) to activate removal and repair of

Christian Zierhut (@zierlab) 's Twitter Profile Photo

The lab’s first pre-print is out! ‘A microscopy reporter for cGAMP reveals rare cGAS activation following DNA damage, and a lack of correlation with micronuclear cGAS enrichment’ biorxiv.org/content/10.110…

Thijn Brummelkamp (@thijnbrummel) 's Twitter Profile Photo

How does DNA damage cause apoptosis when p53 is mutated? Critical to understand treatment of many tumors. Excited that ‘DNA damage induces p53-independent apoptosis through ribosome stalling’ by Nicolaas Boon and collaborators is out: doi.org/10.1126/scienc…

How does DNA damage cause apoptosis when p53 is mutated? Critical to understand treatment of many tumors. Excited that ‘DNA damage induces p53-independent apoptosis through ribosome stalling’ by Nicolaas Boon and collaborators is out: doi.org/10.1126/scienc…
Costa Lab (@costalabcrick) 's Twitter Profile Photo

How does Mcm10 activate an origin of replication? Find the answer in our paper published today in NatureStructMolBiol. Congratulations to Sarah Henrikus & our fantastic lab! 🥳🎉 rdcu.be/dIdI4 Great collaboration with Marta, Allie and John from John Diffley The Francis Crick Institute

How does Mcm10 activate an origin of replication? 

Find the answer in our paper published today in <a href="/NatureSMB/">NatureStructMolBiol</a>. Congratulations to Sarah Henrikus &amp; our fantastic lab! 🥳🎉

rdcu.be/dIdI4

Great collaboration with Marta, Allie and John from <a href="/DiffleyLab/">John Diffley</a> <a href="/TheCrick/">The Francis Crick Institute</a>
Moldovan Lab (@moldovanlab) 's Twitter Profile Photo

Grateful for the opportunity to present our work this week, and happy to see three other former graduate students of the late Stefan Jentsch on this list PfanderLab Rapé Lab @stingele_lab. This one is for you, Stefan!

Cejka Lab (@cejkalab) 's Twitter Profile Photo

Check out our latest paper showing that HLTF removes Cas9 from DNA, explaining phenotypic differences when using the two Cas9 nickase variants. Important for gene editing! Thanks to Giordano Reginato & Rosaria and @MartinJinek Taekjip Ha andre nussenzweig lab nature.com/articles/s4146…

The EMBO Journal (@embojournal) 's Twitter Profile Photo

CMG helicase disassembly is essential and driven by two pathways in budding yeast Karim Labib and colleagues show that Pif1-family helicases mediate an ancestral pathway for ‘old’ #replisome disassembly during the subsequent S-phase embopress.org/doi/full/10.10…

CMG helicase disassembly is essential and driven by two pathways in budding yeast
Karim Labib and colleagues show that Pif1-family helicases mediate an ancestral pathway for ‘old’ #replisome disassembly during the subsequent S-phase
embopress.org/doi/full/10.10…
IMPRS for Living Matter (@imprs_lm) 's Twitter Profile Photo

📢Are you eager to join an international community of scientists to tackle novel and exciting research projects in the areas of #biochemistry, #structuralbiology, #cellbiology, #chemicalbiology and #syntheticbiology? Applications for the IMPRS for Living Matter #PhDprogram are now OPEN!!!

📢Are you eager to join an international community of scientists to tackle novel and exciting research projects in the areas of #biochemistry, #structuralbiology, #cellbiology, #chemicalbiology and #syntheticbiology? Applications for the <a href="/IMPRS_LM/">IMPRS for Living Matter</a> #PhDprogram are now OPEN!!!
Björn Schumacher (@schumacherbj) 's Twitter Profile Photo

Pleasure to host the 2024 meeting of the German Society for DNA Repair ⁦MPI for Biology of Ageing⁩ ⁦CECAD Cologne⁩ in Cologne with outstanding international guest speakers and the amazing community of DNA repair researchers in Germany with ⁦@spanier55⁩ ⁦⁦PfanderLab

Pleasure to host the 2024 meeting of the German Society for DNA Repair ⁦<a href="/MPIAGE/">MPI for Biology of Ageing</a>⁩ ⁦<a href="/CECAD_/">CECAD Cologne</a>⁩ in Cologne with outstanding international guest speakers and the amazing community of DNA repair researchers in Germany with ⁦@spanier55⁩ ⁦⁦<a href="/PfanderLab/">PfanderLab</a>⁩
IMPRS for Living Matter (@imprs_lm) 's Twitter Profile Photo

An intact genetic information is the fundament of life. If you are interested to apply precision genome engineering and state-of-the-art sequencing technology join the PfanderLab IMPRS for Living Matter #PhDposition #IMPRS #cellbiology #DNAreplication #genomeengineering

An intact genetic information is the fundament of life. If you are interested to apply precision genome engineering and state-of-the-art sequencing technology join the <a href="/PfanderLab/">PfanderLab</a> <a href="/IMPRS_LM/">IMPRS for Living Matter</a>
#PhDposition #IMPRS #cellbiology #DNAreplication #genomeengineering
Björn Schumacher (@schumacherbj) 's Twitter Profile Photo

Congratulations to the best poster prize winners Vanessa Borges-Pires, Anita Jopkiewicz, Jessica Spindler, Maximilian Götz, Na Wei, George Galea of the German Society for DNA repair DGDR meeting 2024 in Cologne MPI for Biology of Ageing Cologne Graduate School of Ageing Research CECAD Cologne Universität zu Köln @spanier55 PfanderLab

Congratulations to the best poster prize winners Vanessa Borges-Pires, Anita Jopkiewicz, Jessica Spindler, Maximilian Götz, Na Wei, George Galea of the German Society for DNA repair DGDR meeting 2024 in Cologne <a href="/MPIAGE/">MPI for Biology of Ageing</a> <a href="/CGA_age/">Cologne Graduate School of Ageing Research</a> <a href="/CECAD_/">CECAD Cologne</a> <a href="/UniCologne/">Universität zu Köln</a> @spanier55 <a href="/PfanderLab/">PfanderLab</a>
Fusion Conferences (@fusion_conf) 's Twitter Profile Photo

Roger Greenberg we are really looking forward to your presentation at #DDRCT25 in Lisbon🌞 Registration is OPEN and we have short talk spaces available. 📣Help us spread the word - Please RT to let your followers know! Thank you! Find out more: bit.ly/3BTmZbQ

<a href="/RogerRogergr/">Roger Greenberg</a> we are really looking forward to your presentation at #DDRCT25 in Lisbon🌞
Registration is OPEN and we have short talk spaces available. 📣Help us spread the word - Please RT to let your followers know! Thank you!  
Find out more: bit.ly/3BTmZbQ
ConstantinouLab (@constantinoul) 's Twitter Profile Photo

We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home/

We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home/